Human saliva collection devices for proteomics: an update

Z Khurshid, S Zohaib, S Najeeb, MS Zafar… - International journal of …, 2016 - mdpi.com
There has been a rapid growth in the interest and adaptation of saliva as a diagnostic
specimen over the last decade, and in the last few years in particular, there have been major …

Risk factors in periodontology: a conceptual framework

P Bouchard, MC Carra, A Boillot… - Journal of clinical …, 2017 - Wiley Online Library
Aim The definition and assessment of risk factors, risk indicators and predisposing factors
are of paramount importance in the understanding of the pathogenesis of periodontitis, as …

Salivary type I collagen degradation end‐products and related matrix metalloproteinases in periodontitis

UK Gursoy, E Könönen, S Huumonen… - Journal of clinical …, 2013 - Wiley Online Library
Aim Type I collagen degradation end‐products and related matrix metalloproteinases (MMP
s) were examined aiming to detect potential markers of periodontitis in saliva, with high …

Protein‐based salivary profiles as novel biomarkers for oral diseases

AI Lorenzo-Pouso, M Pérez-Sayáns, SB Bravo… - Disease …, 2018 - Wiley Online Library
The Global Burden of Oral Diseases affects 3.5 billion people worldwide, representing the
number of people affected by the burden of untreated dental caries, severe periodontal …

One decade of salivary proteomics: current approaches and outstanding challenges

FML Amado, RP Ferreira, R Vitorino - Clinical biochemistry, 2013 - Elsevier
Efforts have been made in the last decade towards the complete characterization of saliva
proteome using gel-based and gel-free approaches. The combination of these strategies …

Metaproteome and metabolome of oral microbial communities

N Bostanci, M Grant, K Bao, A Silbereisen… - Periodontology …, 2021 - Wiley Online Library
The emergence of high‐throughput technologies for the comprehensive measurement of
biomolecules, also referred to as “omics” technologies, has helped us gather “big data” and …

Uncovering the molecular networks in periodontitis

F Trindade, FG Oppenheim… - PROTEOMICS …, 2014 - Wiley Online Library
Periodontitis is a complex immune‐inflammatory disease that results from a preestablished
infection in gingiva, mainly due to Gram‐negative bacteria that colonize deeper in gingival …

Identification of periodontitis associated changes in the proteome of whole human saliva by mass spectrometric analysis

MG Salazar, N Jehmlich, A Murr… - Journal of clinical …, 2013 - Wiley Online Library
Aim Interest in human saliva proteomics for disease‐specific biomarker screening increased
in the last decade. We used whole saliva samples from periodontally healthy and diseased …

Advances of proteomic sciences in dentistry

Z Khurshid, S Zohaib, S Najeeb, MS Zafar… - International journal of …, 2016 - mdpi.com
Applications of proteomics tools revolutionized various biomedical disciplines such as
genetics, molecular biology, medicine, and dentistry. The aim of this review is to highlight the …

Host‐microbe interactions: profiles in the transcriptome, the proteome, and the metabolome

T Nguyen, L Sedghi, S Ganther, E Malone… - Periodontology …, 2020 - Wiley Online Library
Periodontal studies using transcriptomics, proteomics, and metabolomics encompass the
collection of mRNA transcripts, proteins, and small‐molecule chemicals in the context of …