Optical studies of single molecules at room temperature
XS **e, JK Trautman - Annual review of physical chemistry, 1998 - annualreviews.org
▪ Abstract Recent developments in optical studies of single molecules at room temperature
are reviewed, with an emphasis on the underlying principles and the potential of single …
are reviewed, with an emphasis on the underlying principles and the potential of single …
Optical detection of single molecules
▪ Abstract Recent advances in ultrasensitive instrumentation have allowed for the detection,
identification, and dynamic studies of single molecules in the condensed phase. This …
identification, and dynamic studies of single molecules in the condensed phase. This …
Single-molecule enzymatic dynamics
Enzymatic turnovers of single cholesterol oxidase molecules were observed in real time by
monitoring the emission from the enzyme's fluorescent active site, flavin adenine …
monitoring the emission from the enzyme's fluorescent active site, flavin adenine …
Detection of intensity change points in time-resolved single-molecule measurements
LP Watkins, H Yang - The Journal of Physical Chemistry B, 2005 - ACS Publications
We present a method for the analysis of optical single molecule emission data that exhibit
discrete intensity jumps. This new method uses a generalized likelihood ratio test that …
discrete intensity jumps. This new method uses a generalized likelihood ratio test that …
Direct observation of molecular cooperativity near the glass transition
E Vidal Russell, NE Israeloff - Nature, 2000 - nature.com
The increasingly sluggish response of a supercooled liquid as it nears its glass transition (for
example, refrigerated honey) is prototypical of glassy dynamics found in proteins, neural …
example, refrigerated honey) is prototypical of glassy dynamics found in proteins, neural …
Single-molecule michaelis− menten equations
This paper summarizes our present theoretical understanding of single-molecule kinetics
associated with the Michaelis− Menten mechanism of enzymatic reactions. Single-molecule …
associated with the Michaelis− Menten mechanism of enzymatic reactions. Single-molecule …
Fluctuating enzymes: lessons from single-molecule studies
Recent single-molecule enzymology measurements with improved statistics have
demonstrated that a single enzyme molecule exhibits large temporal fluctuations of the …
demonstrated that a single enzyme molecule exhibits large temporal fluctuations of the …
Viscoelastic subdiffusion: generalized Langevin equation approach
I Goychuk - Advances in Chemical Physics, 2012 - Wiley Online Library
Viscoelastic subdiffusion: generalized Langevin equation approach Page 195 VISCOELASTIC
SUBDIFFUSION: GENERALIZED LANGEVIN EQUATION APPROACH IGOR GOYCHUK …
SUBDIFFUSION: GENERALIZED LANGEVIN EQUATION APPROACH IGOR GOYCHUK …
Theory of single-molecule spectroscopy: beyond the ensemble average
▪ Abstract Single-molecule spectroscopy (SMS) is a powerful experimental technique used
to investigate a wide range of physical, chemical, and biophysical phenomena. The merit of …
to investigate a wide range of physical, chemical, and biophysical phenomena. The merit of …
Single-molecule enzymology
Viewing a movie of an enzyme molecule made by molecular dynamics simulation, we see
incredible details of molecular motions, be they changes of the conformation or actions …
incredible details of molecular motions, be they changes of the conformation or actions …