Reversal of multidrug resistance by stimuli-responsive drug delivery systems for therapy of tumor
Q Yin, J Shen, Z Zhang, H Yu, Y Li - Advanced drug delivery reviews, 2013 - Elsevier
Multidrug resistance (MDR) is a major obstacle to successful cancer therapy, especially for
chemotherapy. The new drug delivery system (DDS) provides promising approaches to …
chemotherapy. The new drug delivery system (DDS) provides promising approaches to …
The headgroup evolution of cationic lipids for gene delivery
D Zhi, S Zhang, S Cui, Y Zhao, Y Wang… - Bioconjugate …, 2013 - ACS Publications
Cationic lipids are one of the most widely used nonviral vectors for gene delivery and are
especially attractive because they can be easily synthesized and extensively characterized …
especially attractive because they can be easily synthesized and extensively characterized …
A review on cationic lipids with different linkers for gene delivery
D Zhi, Y Bai, J Yang, S Cui, Y Zhao, H Chen… - Advances in colloid and …, 2018 - Elsevier
Cationic lipids have become known as one of the most versatile tools for the delivery of
DNA, RNA and many other therapeutic molecules, and are especially attractive because …
DNA, RNA and many other therapeutic molecules, and are especially attractive because …
Cholesterol modified self-assemblies and their application to nanomedicine
Cholesterol is a ubiquitous molecule in biological systems, and in particular plays various
important roles in mammalian cellular processes. The presence of cholesterol is integral to …
important roles in mammalian cellular processes. The presence of cholesterol is integral to …
Protein and mRNA delivery enabled by cholesteryl‐based biodegradable lipidoid nanoparticles
Develo** safe and efficient delivery systems for therapeutic biomacromolecules is a long‐
standing challenge. Herein, we report a newly developed combinatorial library of cholesteryl …
standing challenge. Herein, we report a newly developed combinatorial library of cholesteryl …
Effective gene delivery using stimulus-responsive catiomer designed with redox-sensitive disulfide and acid-labile imine linkers
A dual stimulus-responsive mPEG-SS-PLL15-glutaraldehyde star (mPEG-SS-PLL15-star)
catiomer is developed and biologically evaluated. The catiomer system combines redox …
catiomer is developed and biologically evaluated. The catiomer system combines redox …
Synthetic nucleic acid delivery systems: present and perspectives
Self-assembled synthetic gene delivery systems represent the bottom-up approach to gene
delivery and gene silencing, in which scientists are designing novel cationic and procationic …
delivery and gene silencing, in which scientists are designing novel cationic and procationic …
The varied influences of cell adhesion and spreading on gene transfection of mesenchymal stem cells on a micropatterned substrate
Transmembrane transport of exogenous genes is widely investigated because of high
demand for gene therapy. Both gene carriers and cellular conditions can affect gene …
demand for gene therapy. Both gene carriers and cellular conditions can affect gene …
Development of self-assembling peptide nanovesicle with bilayers for enhanced EGFR-targeted drug and gene delivery
X Liang, B Shi, K Wang, M Fan, D Jiao, J Ao, N Song… - Biomaterials, 2016 - Elsevier
Abstract Development of rational vectors for efficient drug and gene delivery is crucial for
cancer treatment. In this study, epidermal growth factor receptor (EGFR)-binding peptide …
cancer treatment. In this study, epidermal growth factor receptor (EGFR)-binding peptide …
Novel imidazole-functionalized cyclen cationic lipids: synthesis and application as non-viral gene vectors
Q Liu, QQ Jiang, WJ Yi, J Zhang, XC Zhang… - Bioorganic & medicinal …, 2013 - Elsevier
A series of novel 1, 4, 7, 10-tetraazacyclododecanes (cyclen)-based cationic lipids bearing
histidine imidazole group 10a–10e were synthesized. These amphiphilic molecules have …
histidine imidazole group 10a–10e were synthesized. These amphiphilic molecules have …