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Clinical management of metastatic colorectal cancer in the era of precision medicine
Colorectal cancer (CRC) represents approximately 10% of all cancers and is the second
most common cause of cancer deaths. Initial clinical presentation as metastatic CRC …
most common cause of cancer deaths. Initial clinical presentation as metastatic CRC …
Comprehensive review of targeted therapy for colorectal cancer
YH **e, YX Chen, JY Fang - Signal transduction and targeted therapy, 2020 - nature.com
Colorectal cancer (CRC) is among the most lethal and prevalent malignancies in the world
and was responsible for nearly 881,000 cancer-related deaths in 2018. Surgery and …
and was responsible for nearly 881,000 cancer-related deaths in 2018. Surgery and …
Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆
Colorectal cancer (CRC) is the third most common cancer worldwide, with 1.1 million new
cases per year, and is the second leading cause of cancer death. 1 CRC occurs more …
cases per year, and is the second leading cause of cancer death. 1 CRC occurs more …
Preoperative chemotherapy for operable colon cancer: mature results of an international randomized controlled trial
PURPOSE Neoadjuvant chemotherapy (NAC) has potential advantages over standard
postoperative chemotherapy for locally advanced colon cancer but requires formal …
postoperative chemotherapy for locally advanced colon cancer but requires formal …
Colon cancer, version 3.2024, NCCN clinical practice guidelines in oncology
AB Benson, AP Venook, M Adam, G Chang… - Journal of the National …, 2024 - jnccn.org
Colorectal cancer (CRC) is the fourth most frequently diagnosed cancer and the second
leading cause of cancer death in the United States. Management of disseminated metastatic …
leading cause of cancer death in the United States. Management of disseminated metastatic …
Tumor-derived lactate promotes resistance to bevacizumab treatment by facilitating autophagy enhancer protein RUBCNL expression through histone H3 lysine 18 …
Bevacizumab plays an important role in the first and second line treatment for metastatic
colorectal cancer (CRC). And induction of hypoxia and the tumors response to it plays an …
colorectal cancer (CRC). And induction of hypoxia and the tumors response to it plays an …
Colon cancer, version 2.2021, NCCN clinical practice guidelines in oncology
AB Benson, AP Venook, MM Al-Hawary… - Journal of the National …, 2021 - jnccn.org
This selection from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines)
for Colon Cancer focuses on systemic therapy options for the treatment of metastatic …
for Colon Cancer focuses on systemic therapy options for the treatment of metastatic …
Precision oncology in metastatic colorectal cancer—from biology to medicine
Remarkable progress has been made in the development of biomarker-driven targeted
therapies for patients with multiple cancer types, including melanoma, breast and lung …
therapies for patients with multiple cancer types, including melanoma, breast and lung …
Pathological features and prognostication in colorectal cancer
The prognostication of colorectal cancer (CRC) has traditionally relied on staging as defined
by the Union for International Cancer Control (UICC) and American Joint Committee on …
by the Union for International Cancer Control (UICC) and American Joint Committee on …
Targeted therapy for colorectal cancer metastases: A review of current methods of molecularly targeted therapy and the use of tumor biomarkers in the treatment of …
S Piawah, AP Venook - Cancer, 2019 - Wiley Online Library
Despite recent advances in the management of colorectal cancer, metastatic disease
remains challenging, and patients are rarely cured. However, a better understanding of the …
remains challenging, and patients are rarely cured. However, a better understanding of the …