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Chalcone hybrids as potential anticancer agents: Current development, mechanism of action, and structure‐activity relationship
F Gao, G Huang, J **ao - Medicinal research reviews, 2020 - Wiley Online Library
The continuous emergency of drug‐resistant cancers and the low specificity of anticancer
agents have been the major challenges in the control and treatment of cancer, making an …
agents have been the major challenges in the control and treatment of cancer, making an …
Antibacterial potential of chalcones and its derivatives against Staphylococcus aureus
L da Silva, IA Donato, CAC Gonçalves, JR Scherf… - 3 Biotech, 2023 - Springer
Chalcones are natural substances found in the metabolism of several botanical families.
Their structure consists of 1, 3-diphenyl-2-propen-1-one and they are characterized by …
Their structure consists of 1, 3-diphenyl-2-propen-1-one and they are characterized by …
Ramachary-Bressy-Wang [3+ 2] cycloaddition reaction: Synthesis of fully decorated 1, 2, 3-triazoles as potent anticancer and EGFR inhibitors
M Kumar, SK Nukala, NS Thirukovela… - Journal of Molecular …, 2022 - Elsevier
A general strategy was developed for the synthesis of new fully decorated 1, 2, 3-triazoles
(5a-m & 6a-e) containing coumarine and sulfonyl-benzimidazole from 3-(2-((1-methyl-1H …
(5a-m & 6a-e) containing coumarine and sulfonyl-benzimidazole from 3-(2-((1-methyl-1H …
Synthesis, spectroscopic characterization, DFT analysis, antibacterial, antifungal, antioxidant, molecular docking, and ADME study of 3, 4-dihydro-2H-napthalen-1-one …
RA Shinde, VA Adole, RA More, BS Jagdale… - Journal of Molecular …, 2025 - Elsevier
Chalcone derivatives were synthesized from 3, 4-dihydro-2H-naphthalen-1-one using a
base-catalyzed Claisen-Schmidt reaction and characterized by FT-IR, ¹H NMR, and ¹³C …
base-catalyzed Claisen-Schmidt reaction and characterized by FT-IR, ¹H NMR, and ¹³C …
Design, Synthesis, In Vitro Evaluation and Docking Studies of Pyrazole‐Thiazole Hybrids as Antimicrobial and Antibiofilm Agents
In the present study, a series of novel pyrazole‐thiazole hybrids (4a‐l) were designed,
synthesized and assessed for their in vitro antimicrobial activity against both Gram‐positive …
synthesized and assessed for their in vitro antimicrobial activity against both Gram‐positive …
First synthesis of merged hybrids phosphorylated azirino [2, 1-b] benzo [e][1, 3] oxazine derivatives as anticancer agents
V Carraminana, AMO de Retana… - European Journal of …, 2020 - Elsevier
This work describes a straightforward diastereoselective synthetic access to azirino [2, 1-b]
benzo [e][1, 3] oxazines containing phosphorus substituents such as phosphonate or …
benzo [e][1, 3] oxazines containing phosphorus substituents such as phosphonate or …
Synthesis and biological evaluation of cyanoaziridine phosphine oxides and phosphonates with antiproliferative activity
V Carramiñana, AMO de Retana, AV Del Burgo… - European Journal of …, 2019 - Elsevier
This work reports an efficient diastereoselective synthetic methodology for the preparation of
phosphorus substituted cyanoaziridines through the nucleophilic addition of TMSCN, as …
phosphorus substituted cyanoaziridines through the nucleophilic addition of TMSCN, as …
Recent advances in chalcone-based anticancer heterocycles: A structural and molecular target perspective
V Kumar, S Dhawan, PS Girase… - Current Medicinal …, 2021 - benthamdirect.com
Chalcones are an interesting class of compounds endowed with a plethora of biological
activities beneficial to human health. These chemotypes have continued to attract increased …
activities beneficial to human health. These chemotypes have continued to attract increased …
[HTML][HTML] Synthesis of α-Aminophosphonic Acid Derivatives Through the Addition of O- and S-Nucleophiles to 2H-Azirines and Their Antiproliferative Effect on A549 …
V Carramiñana, AM Ochoa de Retana, F Palacios… - Molecules, 2020 - mdpi.com
This work reports a straightforward regioselective synthetic methodology to prepare α-
aminophosphine oxides and phosphonates through the addition of oxygen and sulfur …
aminophosphine oxides and phosphonates through the addition of oxygen and sulfur …
3‐Bromoacetylcoumarin, a Crucial Key for Facial Synthesis of Biological Active Compounds
Compounds containing the coumarin scaffold are widely used in the pharmaceutical and
medicinal industries. The biological activities of coumarin containing derivatives make the …
medicinal industries. The biological activities of coumarin containing derivatives make the …