A comprehensive metabolic map for production of bio-based chemicals

SY Lee, HU Kim, TU Chae, JS Cho, JW Kim, JH Shin… - Nature …, 2019 - nature.com
Production of industrial chemicals using renewable biomass feedstock is becoming
increasingly important to address limited fossil resources, climate change and other …

Applications of genome‐scale metabolic reconstructions

MA Oberhardt, BØ Palsson, JA Papin - Molecular systems biology, 2009 - embopress.org
The availability and utility of genome‐scale metabolic reconstructions have exploded since
the first genome‐scale reconstruction was published a decade ago. Reconstructions have …

Yeast systems biology: model organism and cell factory

J Nielsen - Biotechnology journal, 2019 - Wiley Online Library
For thousands of years, the yeast Saccharomyces cerevisiae (S. cerevisiae) has served as a
cell factory for the production of bread, beer, and wine. In more recent years, this yeast has …

Recovery of carboxylic acids produced by fermentation

CS López-Garzón, AJJ Straathof - Biotechnology advances, 2014 - Elsevier
Carboxylic acids such as citric, lactic, succinic and itaconic acids are useful products and are
obtained on large scale by fermentation. This review describes the options for recovering …

Valorization of industrial waste and by-product streams via fermentation for the production of chemicals and biopolymers

AA Koutinas, A Vlysidis, D Pleissner… - Chemical Society …, 2014 - pubs.rsc.org
The transition from a fossil fuel-based economy to a bio-based economy necessitates the
exploitation of synergies, scientific innovations and breakthroughs, and step changes in the …

Recent advances in metabolic engineering of Saccharomyces cerevisiae: new tools and their applications

J Lian, S Mishra, H Zhao - Metabolic engineering, 2018 - Elsevier
Metabolic engineering aims to develop efficient cell factories by rewiring cellular
metabolism. As one of the most commonly used cell factories, Saccharomyces cerevisiae …

The role of yeasts and lactic acid bacteria on the metabolism of organic acids during winemaking

A Mendes Ferreira, A Mendes-Faia - Foods, 2020 - mdpi.com
The main role of acidity and pH is to confer microbial stability to wines. No less relevant, they
also preserve the color and sensory properties of wines. Tartaric and malic acids are …

Organic acids as antimicrobial food agents: applications and microbial productions

HB Coban - Bioprocess and Biosystems Engineering, 2020 - Springer
Food safety is a global health and socioeconomic concern since many people still suffer
from various acute and life-long diseases, which are caused by consumption of unsafe food …

Metabolic engineering in methanotrophic bacteria

MG Kalyuzhnaya, AW Puri, ME Lidstrom - Metabolic engineering, 2015 - Elsevier
Methane, as natural gas or biogas, is the least expensive source of carbon for (bio) chemical
synthesis. Scalable biological upgrading of this simple alkane to chemicals and fuels can …

Bio‐based production of C2–C6 platform chemicals

YS Jang, B Kim, JH Shin, YJ Choi… - Biotechnology and …, 2012 - Wiley Online Library
Platform chemicals composed of 2–6 carbons derived from fossil resources are used as
important precursors for making a variety of chemicals and materials, including solvents …