In recent years, sensory neuroscientists have made major efforts to dissect the structure and
function of ribbon synapses which process sensory information in the eye and ear. This …

The physical distance between presynaptic Ca2+ channels and the Ca2+ sensors that
trigger exocytosis of neurotransmitter-containing vesicles is a key determinant of the …

Sensory synapses of the visual and auditory systems must faithfully encode a wide dynamic
range of graded signals, and must be capable of sustained transmitter release over long …

Amacrine cells represent the most diverse class of retinal neuron, comprising dozens of
distinct cell types. Each type exhibits a unique morphology and generates specific visual …

Cochlear inner hair cells (IHC s) develop from pre‐sensory pacemaker to sound transducer.
Here, we report that this involves changes in structure and function of the ribbon synapses …

Calcium influx through voltage-gated Ca (CaV) channels is the first step in synaptic
transmission. This review concerns CaV channels at ribbon synapses in primary sense …

Hair cell ribbon synapses exhibit several distinguishing features. Structurally, a dense body,
or ribbon, is anchored to the presynaptic membrane and tethers synaptic vesicles; …

Synaptic ribbons are large proteinaceous scaffolds at the active zone of ribbon synapses
that are specialized for rapid sustained synaptic vesicles exocytosis. A single ribbon‐specific …

We studied the role of the synaptic ribbon for sound encoding at the synapses between
inner hair cells (IHCs) and spiral ganglion neurons (SGNs) in mice lacking RIBEYE …

Components of neural circuits are often repurposed so that the same biological hardware
can be used for distinct computations. This flexibility in circuit operation is required to …