Bacterial chemotaxis in human diseases

B Zhou, CM Szymanski, A Baylink - Trends in Microbiology, 2023 - cell.com
To infect and cause disease, bacterial pathogens must localize to specific regions of the host
where they possess the metabolic and defensive acumen for survival. Motile flagellated …

Structure and function of microbial α-l-fucosidases: a mini review

H Wu, CD Owen, N Juge - Essays in Biochemistry, 2023 - portlandpress.com
Fucose is a monosaccharide commonly found in mammalian, insect, microbial and plant
glycans. The removal of terminal α-l-fucosyl residues from oligosaccharides and …

Human gut bacteria tailor extracellular vesicle cargo for the breakdown of diet-and host-derived glycans

MG Sartorio, EJ Pardue, NE Scott… - Proceedings of the …, 2023 - pnas.org
Extracellular vesicles are produced in all three domains of life, and their biogenesis has
common ancient origins in eukaryotes and archaea. Although bacterial vesicles were …

Revisiting Campylobacter jejuni Virulence and Fitness Factors: Role in Sensing, Adapting, and Competing

A Elmi, F Nasher, N Dorrell, B Wren… - Frontiers in cellular and …, 2021 - frontiersin.org
Campylobacter jejuni is the leading cause of bacterial foodborne gastroenteritis world wide
and represents a major public health concern. Over the past two decades, significant …

Significance of fucose in intestinal health and disease

JM Garber, T Hennet, CM Szymanski - Molecular Microbiology, 2021 - Wiley Online Library
The deoxyhexose sugar L‐fucose is important for many biological processes within the
human body and the associated microbiota. This carbohydrate is abundant in host gut …

Microbial adaptation to the healthy and inflamed gut environments

Y Guo, S Kitamoto, N Kamada - Gut microbes, 2020 - Taylor & Francis
There are 100 trillion diverse bacterial residents in the mammalian gut. Commensal
bacterial species/strains cooperate and compete with each other to establish a well …

The bidirectional nature of microbiome-epithelial cell interactions

AG Solis, M Klapholz, J Zhao, M Levy - Current opinion in microbiology, 2020 - Elsevier
The biogeography of the mammalian intestine is remarkable in that a vast microbial
consortium exists inside the organism, surrounded by intestinal epithelial cells. The …

Sialylation and fucosylation modulate inflammasome-activating eIF2 Signaling and microbial translocation during HIV infection

LB Giron, CE Tanes, MH Schleimann, PA Engen… - Mucosal …, 2020 - nature.com
An emerging paradigm suggests that gut glycosylation is a key force in maintaining the
homeostatic relationship between the gut and its microbiota. Nevertheless, it is unclear how …

[HTML][HTML] Catabolic network of the fermentative gut bacterium Phocaeicola vulgatus (phylum Bacteroidota) from a physiologic-proteomic perspective

U Clausen, ST Vital, P Lambertus, M Gehler… - Microbial …, 2024 - karger.com
Abstract Introduction: Phocaeicola vulgatus (formerly Bacteroides vulgatus) is a prevalent
member of human and animal guts, where it influences by its dietary-fiber-fueled …

Crystal structure of l-2-keto-3-deoxyfuconate 4-dehydrogenase reveals a unique binding mode as a α-furanosyl hemiketal of substrates

M Akagashi, S Watanabe, S Kwiatkowski, J Drozak… - Scientific Reports, 2024 - nature.com
Abstract l-2-Keto-3-deoxyfuconate 4-dehydrogenase (l-KDFDH) catalyzes the NAD+-
dependent oxidization of l-2-keto-3-deoxyfuconate (l-KDF) to l-2, 4-diketo-3-deoxyfuconate (l …