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Antibiotics in the clinical pipeline as of December 2022
The need for new antibacterial drugs to treat the increasing global prevalence of drug-
resistant bacterial infections has clearly attracted global attention, with a range of existing …
resistant bacterial infections has clearly attracted global attention, with a range of existing …
Antibiotics in the clinical pipeline in October 2019
The development of new and effective antibacterial drugs to treat multi-drug resistant (MDR)
bacteria, especially Gram-negative (G− ve) pathogens, is acknowledged as one of the …
bacteria, especially Gram-negative (G− ve) pathogens, is acknowledged as one of the …
QSPR analysis of distance-based structural indices for drug compounds in tuberculosis treatment
Tuberculosis (TB) is one of the most contagious diseases that has a greater mortality rate
than HIV/AIDS and the cases of TB are feared to rise as a repercussion of the COVID-19 …
than HIV/AIDS and the cases of TB are feared to rise as a repercussion of the COVID-19 …
MDR tuberculosis treatment
J Espinosa-Pereiro, A Sánchez-Montalvá, ML Aznar… - Medicina, 2022 - mdpi.com
Multidrug-resistant (MDR) tuberculosis (TB), resistant to isoniazid and rifampicin, continues
to be one of the most important threats to controlling the TB epidemic. Over the last few …
to be one of the most important threats to controlling the TB epidemic. Over the last few …
Tuberculosis challenges: Resistance, co-infection, diagnosis, and treatment
Early diagnosis of tuberculosis (TB), followed by effective treatment, is the cornerstone of
global TB control efforts. An estimated 3 million cases of TB remain undetected each year …
global TB control efforts. An estimated 3 million cases of TB remain undetected each year …
Comprehensive review on mechanism of action, resistance and evolution of antimycobacterial drugs
Tuberculosis is one of the deadliest infectious diseases existing in the world since ancient
times and still possesses serious threat across the globe. Each year the number of cases …
times and still possesses serious threat across the globe. Each year the number of cases …
Synthesis and characterization of new N-acyl hydrazone derivatives of carprofen as potential tuberculostatic agents
N-acyl hydrazone (NAH) is recognized as a promising framework in drug design due to its
versatility, straightforward synthesis, and attractive range of biological activities, including …
versatility, straightforward synthesis, and attractive range of biological activities, including …
[HTML][HTML] Tuberculosis: Past, present and future of the treatment and drug discovery research
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium
tuberculosis. Despite decades of research driving advancements in drug development and …
tuberculosis. Despite decades of research driving advancements in drug development and …
Recent advances in nanoplatforms for the treatment of osteosarcoma
K Wu, B Yu, D Li, Y Tian, Y Liu, J Jiang - Frontiers in Oncology, 2022 - frontiersin.org
Osteosarcoma (OS) is the most common primary bone tumor in children and young people.
Traditional surgical excision combined with chemotherapy presents many limitations, such …
Traditional surgical excision combined with chemotherapy presents many limitations, such …
Recent advancements and developments in search of anti-tuberculosis agents: a quinquennial update and future directions
Tuberculosis (TB) has been considered as the highly chronic, contagious and infectious
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …