Using zebrafish in systems toxicology for developmental toxicity testing

Y Nishimura, A Inoue, S Sasagawa… - Congenital …, 2016 - Wiley Online Library
With the high cost and the long‐term assessment of developmental toxicity testing in
mammals, the vertebrate zebrafish has become a useful alternative model organism for high …

Review of high-content screening applications in toxicology

S Li, M **a - Archives of toxicology, 2019 - Springer
High-content screening (HCS) technology combining automated microscopy and
quantitative image analysis can address biological questions in academia and the …

Embryonic exposure to butylparaben and propylparaben induced developmental toxicity and triggered anxiety‐like neurobehavioral response associated with …

C Lite, A Guru, M Juliet… - Environmental …, 2022 - Wiley Online Library
Parabens are synthetic antimicrobial compounds used as a preservative for extending the
shelf life of food, pharmaceutical and cosmetic products. The alkyl chain length of the …

[HTML][HTML] Engineering spatial-organized cardiac organoids for developmental toxicity testing

P Hoang, A Kowalczewski, S Sun, TS Winston… - Stem Cell Reports, 2021 - cell.com
Emerging technologies in stem cell engineering have produced sophisticated organoid
platforms by controlling stem cell fate via biomaterial instructive cues. By micropatterning …

Research progress of zebrafish model in aquatic ecotoxicology

H Li, Y Liu, Q Chen, L **, R Peng - Water, 2023 - mdpi.com
In recent years, with the aggravation of environmental pollution, the study of aquatic
ecotoxicology has become a hot topic. Some aquatic organisms, such as large fleas, toads …

Toxicity assessment of 4 azo dyes in zebrafish embryos

LL Jiang, K Li, DL Yan, MF Yang… - … journal of toxicology, 2020 - journals.sagepub.com
Azo dyes are used widely as color additives in food, drugs, and cosmetics; hence, there is
an increasing concern about their safety and possible health hazards. In the present study …

Developmental toxicity caused by sanguinarine in zebrafish embryos via regulating oxidative stress, apoptosis and wnt pathways

X Yang, X Wang, D Gao, Y Zhang, X Chen, Q **a… - Toxicology Letters, 2021 - Elsevier
Sanguinarine, derived from the root of Sanguinaria canadensis, have multiple biological
activities, such as antimicrobial, insecticidal, antitumor, anti-inflammatory and anti …

Identification of side effects of COVID-19 drug candidates on embryogenesis using an integrated zebrafish screening platform

A Ernst, I Piragyte, AM Mp, ND Le, D Grandgirard… - Scientific reports, 2023 - nature.com
Drug repurposing is an important strategy in COVID-19 treatment, but many clinically
approved compounds have not been extensively studied in the context of embryogenesis …

A systematic review of the toxic potential of parabens in fish

AK Dasmahapatra, J Chatterjee… - Frontiers in …, 2024 - frontiersin.org
Parabens are the most prevalent ingredients in cosmetics and personal care products
(PCPs). They are colorless and tasteless and exhibit good stability when combined with …

Developmental toxicity induced by PM2. 5 through endoplasmic reticulum stress and autophagy pathway in zebrafish embryos

Y Zhang, S Li, J Li, L Han, Q He, R Wang, X Wang… - Chemosphere, 2018 - Elsevier
The aims of this study were to investigate the mechanism underlying the developmental
toxicity of fine particulate matter (PM 2.5) and provide a more thorough understanding of the …