Clustered miRNAs and their role in biological functions and diseases
MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …
Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family in physiological and pathophysiological process and diseases
L Qian, Y Zhu, C Deng, Z Liang, J Chen… - … and Targeted Therapy, 2024 - nature.com
Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family (PGC-1s),
consisting of three members encompassing PGC-1α, PGC-1β, and PGC-1-related …
consisting of three members encompassing PGC-1α, PGC-1β, and PGC-1-related …
Exosomal miRNA-19b-3p of tubular epithelial cells promotes M1 macrophage activation in kidney injury
LL Lv, Y Feng, M Wu, B Wang, ZL Li, X Zhong… - Cell Death & …, 2020 - nature.com
Tubulointerstitial inflammation is a common characteristic of acute and chronic kidney injury.
However, the mechanism by which the initial injury of tubular epithelial cells (TECs) drives …
However, the mechanism by which the initial injury of tubular epithelial cells (TECs) drives …
[HTML][HTML] Focus: the science of stress: oxidative stress and inflammation in cardiovascular diseases and cancer: role of non-coding RNAs
P Ginckels, P Holvoet - The Yale Journal of Biology and Medicine, 2022 - ncbi.nlm.nih.gov
Abstract High oxidative stress, Th1/Th17 immune response, M1 macrophage inflammation,
and cell death are associated with cardiovascular diseases. Controlled oxidative stress …
and cell death are associated with cardiovascular diseases. Controlled oxidative stress …
Potential value of miR-221/222 as diagnostic, prognostic, and therapeutic biomarkers for diseases
J Song, Y Ouyang, J Che, X Li, Y Zhao, K Yang… - Frontiers in …, 2017 - frontiersin.org
microRNAs (miRNAs) are short non-coding RNAs that regulate gene expression by base
pairing with their target messenger RNAs. Dysregulation of miRNAs is involved in the …
pairing with their target messenger RNAs. Dysregulation of miRNAs is involved in the …
[HTML][HTML] Perivascular adipose tissue–derived extracellular vesicle miR-221-3p mediates vascular remodeling
Adipose tissue–secreted extracellular vesicles (EVs) containing microRNAs (miRNAs)
convey intercellular message signaling. The biogenesis of EV-miRNAs from perivascular …
convey intercellular message signaling. The biogenesis of EV-miRNAs from perivascular …
Impact of microRNAs on ischemic stroke: from pre-to post-disease
G Li, KC Morris-Blanco, MS Lopez, T Yang… - Progress in …, 2018 - Elsevier
Stroke is the number one cause of neurological dysfunction in adults and has a heavy
socioeconomic burden worldwide. The etiological origins of ischemic stroke and resulting …
socioeconomic burden worldwide. The etiological origins of ischemic stroke and resulting …
[HTML][HTML] Circulating MiR-19b-3p, MiR-134-5p and MiR-186-5p are promising novel biomarkers for early diagnosis of acute myocardial infarction
KJ Wang, X Zhao, YZ Liu, QT Zeng, XB Mao… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Recent studies have shown that circulating microRNAs (miRNAs) are
emerging as promising biomarkers for cardiovascular diseases. This study aimed to …
emerging as promising biomarkers for cardiovascular diseases. This study aimed to …
The mir-221/222 cluster is a key player in vascular biology via the fine-tuning of endothelial cell physiology
The discovery of small RNAs has shed new light on microRNA (mRNA) regulation and a
range of biological processes. The recognition that miRNAs-221 and-222 are sensitive …
range of biological processes. The recognition that miRNAs-221 and-222 are sensitive …
HDAC3 protects against atherosclerosis through inhibition of inflammation via the microRNA-19b/PPARγ/NF-κB axis
J Wang, X Xu, P Li, B Zhang, J Zhang - Atherosclerosis, 2021 - Elsevier
Background and aims Atherosclerosis (AS) is one of the leading causes of cardiovascular
diseases. Studies have revealed critical roles of microRNAs (miRNAs) in the progression of …
diseases. Studies have revealed critical roles of microRNAs (miRNAs) in the progression of …