Natural killer (NK) cells are lymphocytes that contribute to the early immune responses to
viruses. NK cells are innate immune cells that do not express rearranged antigen receptors …

Viruses have evolved precise mechanisms for using the cellular physiological pathways for
their perpetuation. These virus-driven biochemical events must be separated in space and …

Flaviviruses pose a constant threat to human health. These RNA viruses are transmitted by
the bite of infected mosquitoes and ticks and regularly cause outbreaks. To identify host …

The RNA modification N 6-methyladenosine (m 6 A) modulates mRNA fate and thus affects
many biological processes. We analyzed m 6 A across the transcriptome following infection …

Ubiquitylation is one of the most versatile protein post-translational modifications and is
frequently altered during virus infections. Here we employed a functional proteomics screen …

Zika virus (ZIKV) has recently emerged as a global health concern owing to its widespread
diffusion and its association with severe neurological symptoms and microcephaly in …

In recent years the emergence and resurgence of arboviruses have generated a global
health alert. Among arboviruses, Dengue (DENV), Zika (ZIKV), Yellow Fever (YFV), and …

The endoplasmic reticulum (ER) is an architecturally diverse organelle that serves as a
membrane source for the replication of multiple viruses. Flaviviruses, including yellow fever …

Despite tremendous advances in the development of anti-viral therapeutics, viral infections
remain a chief culprit accounting for ongoing morbidity and mortality worldwide. Natural …

The Flavivirus genus consists of> 70 members including several that are considered
significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be …