Forty-five years of Marburg virus research
In 1967, the first reported filovirus hemorrhagic fever outbreak took place in Germany and
the former Yugoslavia. The causative agent that was identified during this outbreak, Marburg …
the former Yugoslavia. The causative agent that was identified during this outbreak, Marburg …
Small molecules targeting viral RNA
T Hermann - Wiley Interdisciplinary Reviews: RNA, 2016 - Wiley Online Library
Highly conserved noncoding RNA (ncRNA) elements in viral genomes and transcripts offer
new opportunities to expand the repertoire of drug targets for the development of …
new opportunities to expand the repertoire of drug targets for the development of …
Marburg virus evades interferon responses by a mechanism distinct from ebola virus
C Valmas, MN Grosch, M Schümann, J Olejnik… - PLoS …, 2010 - journals.plos.org
Previous studies have demonstrated that Marburg viruses (MARV) and Ebola viruses
(EBOV) inhibit interferon (IFN)-α/β signaling but utilize different mechanisms. EBOV inhibits …
(EBOV) inhibit interferon (IFN)-α/β signaling but utilize different mechanisms. EBOV inhibits …
[HTML][HTML] Both matrix proteins of Ebola virus contribute to the regulation of viral genome replication and transcription
Ebola virus (EBOV) causes severe hemorrhagic fevers in humans and non-human primates.
While the role of the EBOV major matrix protein VP40 in morphogenesis is well understood …
While the role of the EBOV major matrix protein VP40 in morphogenesis is well understood …
Ebola virus VP35 antagonizes PKR activity through its C-terminal interferon inhibitory domain
M Schümann, T Gantke, E Mühlberger - Journal of virology, 2009 - Am Soc Microbiol
Ebola virus VP35 contains a C-terminal cluster of basic amino acids required for double-
stranded RNA (dsRNA) binding and inhibition of interferon regulatory factor 3 (IRF3). VP35 …
stranded RNA (dsRNA) binding and inhibition of interferon regulatory factor 3 (IRF3). VP35 …
Distinct genome replication and transcription strategies within the growing filovirus family
AJ Hume, E Mühlberger - Journal of molecular biology, 2019 - Elsevier
Research on filoviruses has historically focused on the highly pathogenic ebola-and
marburgviruses. Indeed, until recently, these were the only two genera in the filovirus family …
marburgviruses. Indeed, until recently, these were the only two genera in the filovirus family …
Reemergence of Marburgvirus disease: update on current control and prevention measures and review of the literature
R Elsheikh, AM Makram, H Selim… - Reviews in Medical …, 2023 - Wiley Online Library
In 1967, the very first case of the Marburgvirus disease (MVD) was detected in Germany and
Serbia sequentially. Since then, MVD has been considered one of the most serious and …
Serbia sequentially. Since then, MVD has been considered one of the most serious and …
Minigenomes, transcription and replication competent virus-like particles and beyond: reverse genetics systems for filoviruses and other negative stranded …
Reverse-genetics systems are powerful tools enabling researchers to study the replication
cycle of RNA viruses, including filoviruses and other hemorrhagic fever viruses, as well as to …
cycle of RNA viruses, including filoviruses and other hemorrhagic fever viruses, as well as to …
Structural basis for Marburg virus VP35–mediated immune evasion mechanisms
P Ramanan, MR Edwards… - Proceedings of the …, 2012 - National Acad Sciences
Filoviruses, marburgvirus (MARV) and ebolavirus (EBOV), are causative agents of highly
lethal hemorrhagic fever in humans. MARV and EBOV share a common genome …
lethal hemorrhagic fever in humans. MARV and EBOV share a common genome …
Filoviral immune evasion mechanisms
P Ramanan, RS Shabman, CS Brown… - Viruses, 2011 - mdpi.com
The Filoviridae family of viruses, which includes the genera Ebolavirus (EBOV) and
Marburgvirus (MARV), causes severe and often times lethal hemorrhagic fever in humans …
Marburgvirus (MARV), causes severe and often times lethal hemorrhagic fever in humans …