Mass spectrometers are versatile sensor systems, owing to their high sensitivity and ability to
simultaneously measure multiple chemical species. Over the last two decades, traditional …

This paper reviews mass spectrometers based on micro-electro-mechanical systems
(MEMS) technology. The MEMS approach to integration is first briefly described, and the …

Analytical chemists are instilled with the Shannon–Nyquist theorem for measuring practices:
the sampling frequency must be greater than two times the frequency of the signal of interest …

Despite many potential applications, miniature mass spectrometers have had limited
adoption in the field due to the tradeoff between throughput and resolution that limits their …

Spatial aperture coding is a technique used to improve throughput without sacrificing
resolution both in optical spectroscopy and sector mass spectrometry (MS). Previous work …

Miniaturizing instruments for spectroscopic applications requires the designer to confront a
tradeoff between instrument resolution and instrument throughput [and associated signal-to …

In order to minimize losses in signal intensity often present in mass spectrometry
miniaturization efforts, we recently applied the principles of spatially coded apertures to …

In 1938, Walker Bleakney and John A. Hipple first described the cycloidal mass analyzer as
the only mass analyzer configuration capable of “perfect” ion focusing. Why has their …

The use of coded apertures in mass spectrometry can break the trade-off between
throughput and resolution that has historically plagued conventional instruments. Despite …

Cycloidal sector mass analyzers have, in principle, perfect focusing due to perpendicularly
oriented uniform electric and magnetic fields, making them ideal candidates for …