In recent years, a population of unconventional T cells called 'mucosal-associated invariant
T cells'(MAIT cells) has captured the attention of immunologists and clinicians due to their …

Immune checkpoint molecules, like CTLA-4, TIM-3, PD-1, are negative regulators of immune
responses to avoid immune injury. Checkpoint regulators are thought to actively participate …

Pregnancy problems including recurrent pregnancy loss, repeated implantation failure and
pre‐eclampsia are common problems in the reproductive ages. Different reasons such as …

Regulatory T (Treg) cells are a specialized subpopulation of T cells that plays critical roles in
the maintenance of immune homeostasis. Although efforts have been done, their role in …

Preeclampsia is a pregnancy-specific disease which is characterized by abnormal
placentation, endothelial dysfunction, and systemic inflammation. Several studies have …

The conception of how the immune system is organized has been significantly challenged
over the last years. It became evident that not all lymphocytes are mobile and recirculate …

Lectin-glycan interactions, in particular those mediated by the galectin family, regulate many
processes required for a successful pregnancy. Over the past decades, increasing evidence …

The immune escape mechanisms at the base of tumor progression in endometrial cancer
mimic immune tolerance mechanisms occurring at the maternal–fetal interface. The …

Oncolytic viruses (OVs) have emerged as a potential strategy for tumor treatment due to their
ability to selectively replicate in tumor cells, induce apoptosis, and stimulate immune …

The intervillous space of the placenta is a part of the fetal-maternal interface, where maternal
blood enters to provide nutrients and gas exchange. Little is known about the maternal …