Lignans and Neolignans: Plant secondary metabolites as a reservoir of biologically active substances

F Zálešák, DJYD Bon, J Pospíšil - Pharmacological Research, 2019 - Elsevier
Lignans and neolignans are plant secondary metabolites derived from the oxidative
coupling of phenylpropanoids. Biological activity of these phenolic compounds ranges from …

An updated review of folate-functionalized nanocarriers: A promising ligand in cancer

P Ebrahimnejad, AS Taleghani, K Asare-Addo… - Drug discovery today, 2022 - Elsevier
The uncontrolled release of drugs in conventional drug delivery systems has led to the
introduction of new nanotechnology-based drug delivery systems and the use of targeted …

Phytochemical screening and antimicrobial activity evaluation of selected medicinal plants in Ethiopia

S Dubale, D Kebebe, A Zeynudin… - Journal of …, 2023 - Taylor & Francis
Background The emergence and spread of resistant microbes continue to be a major public
health concern. Effective treatment alternatives, particularly from traditionally used medicinal …

Marine natural products as source of new drugs: A patent review (2015–2018)

P Shinde, P Banerjee, A Mandhare - Expert opinion on therapeutic …, 2019 - Taylor & Francis
Introduction: Natural products from plants, animals, microbes, and minerals have long been
a traditional source for the treatment of human diseases. In the past decades, research on …

An overview of malaria transmission mechanisms, control, and modeling

MK Savi - Medical Sciences, 2022 - mdpi.com
In sub-Saharan Africa, malaria is a leading cause of mortality and morbidity. As a result of
the interplay between many factors, the control of this disease can be challenging. However …

Innovation in neglected tropical disease drug discovery and development

HB Weng, HX Chen, MW Wang - Infectious diseases of poverty, 2018 - mednexus.org
Background: Neglected tropical diseases (NTDs) are closely related to poverty and affect
over a billion people in develo** countries. The unmet treatment needs cause high …

Plant secondary metabolites: An introduction of their chemistry and biological significance with physicochemical aspect

A Sharma, S Sharma, A Kumar, V Kumar… - … -chemical properties and …, 2022 - Springer
Nature is the immense source of chemical compounds or substances usually acknowledged
as natural products. Plants are the considerable source of an inestimable diversity of natural …

A comprehensive review of chalcone derivatives as antileishmanial agents

MVP de Mello, B de Azevedo Abrahim-Vieira… - European journal of …, 2018 - Elsevier
Leishmaniasis is a group of infectious neglected tropical diseases caused by more than 20
pathogenic species of Leishmania sp. Due to the limitations of the current treatments …

[HTML][HTML] Alkaloids in contemporary drug discovery to meet global disease needs

S Daley, GA Cordell - Molecules, 2021 - mdpi.com
An overview is presented of the well-established role of alkaloids in drug discovery, the
application of more sustainable chemicals, and biological approaches, and the …

Current drug strategies for the treatment and control of schistosomiasis

MA Villamizar-Monsalve, J López-Abán… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Schistosomiasis, one of the current Neglected Tropical Diseases (NTDs) affects
over 230 million people globally, with nearly 700 million at risk in more than 74 countries …