PIWI-interacting RNAs: small RNAs with big functions
In animals, PIWI-interacting RNAs (piRNAs) of 21–35 nucleotides in length silence
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …
piRNA-guided genome defense: from biogenesis to silencing
PIWI-interacting RNAs (piRNAs) and their associated PIWI clade Argonaute proteins
constitute the core of the piRNA pathway. In gonadal cells, this conserved pathway is crucial …
constitute the core of the piRNA pathway. In gonadal cells, this conserved pathway is crucial …
One loop to rule them all: the **-pong cycle and piRNA-guided silencing
The PIWI-interacting RNA (piRNA) pathway is a conserved defense mechanism that protects
the genetic information of animal germ cells from the deleterious effects of molecular …
the genetic information of animal germ cells from the deleterious effects of molecular …
PIWI-interacting RNA: its biogenesis and functions
PIWI-interacting RNAs (piRNAs) are a class of small RNAs that are 24–31 nucleotides in
length. They associate with PIWI proteins, which constitute a germline-specific subclade of …
length. They associate with PIWI proteins, which constitute a germline-specific subclade of …
Argonaute proteins: functional insights and emerging roles
G Meister - Nature Reviews Genetics, 2013 - nature.com
Small-RNA-guided gene regulation has emerged as one of the fundamental principles in
cell function, and the major protein players in this process are members of the Argonaute …
cell function, and the major protein players in this process are members of the Argonaute …
piRNA-guided transposon cleavage initiates Zucchini-dependent, phased piRNA production
PIWI-interacting RNAs (piRNAs) protect the animal germ line by silencing transposons.
Primary piRNAs, generated from transcripts of genomic transposon “junkyards”(piRNA …
Primary piRNAs, generated from transcripts of genomic transposon “junkyards”(piRNA …
Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elements
In animals, small RNA molecules termed PIWI-interacting RNAs (piRNAs) silence
transposable elements (TEs), protecting the germline from genomic instability and mutation …
transposable elements (TEs), protecting the germline from genomic instability and mutation …
A single mechanism of biogenesis, initiated and directed by PIWI proteins, explains piRNA production in most animals
In animals, PIWI-interacting RNAs (piRNAs) guide PIWI proteins to silence transposons and
regulate gene expression. The mechanisms for making piRNAs have been proposed to …
regulate gene expression. The mechanisms for making piRNAs have been proposed to …
Elimination of PCR duplicates in RNA-seq and small RNA-seq using unique molecular identifiers
Background RNA-seq and small RNA-seq are powerful, quantitative tools to study gene
regulation and function. Common high-throughput sequencing methods rely on polymerase …
regulation and function. Common high-throughput sequencing methods rely on polymerase …
The piRNA pathway guards the germline genome against transposable elements
KF Tóth, D Pezic, E Stuwe, A Webster - Non-coding RNA and the …, 2016 - Springer
Transposable elements (TEs) have the capacity to replicate and insert into new genomic
locations. This contributs significantly to evolution of genomes, but can also result in DNA …
locations. This contributs significantly to evolution of genomes, but can also result in DNA …