Role of cues and contexts on drug‐seeking behaviour

CJ Perry, I Zbukvic, JH Kim… - British journal of …, 2014 - Wiley Online Library
Environmental stimuli are powerful mediators of craving and relapse in substance‐abuse
disorders. This review examined how animal models have been used to investigate the …

Nicotine acutely enhances reinforcement from non-drug rewards in humans

KA Perkins, JL Karelitz, MC Boldry - Frontiers in psychiatry, 2017 - frontiersin.org
Preclinical research documents that, aside from the primary and secondary reinforcing
effects of nicotine intake itself, nicotine also acutely enhances the reinforcing efficacy of non …

Association between nicotine withdrawal and reward responsiveness in humans and rats

ML Pergadia, A Der-Avakian, MS D'Souza… - JAMA …, 2014 - jamanetwork.com
Importance Reward-related disturbances after withdrawal from nicotine are hypothesized to
contribute to relapse to tobacco smoking but mechanisms underlying and linking such …

Dissociated effects of anticipating smoking versus monetary reward in the caudate as a function of smoking abstinence

MM Sweitzer, CF Geier, DL Joel, P McGurrin… - Biological …, 2014 - Elsevier
Background Theories of addiction suggest that chronic smoking may be associated with
both hypersensitivity to smoking and related cues and hyposensitivity to alternative …

Smoking abstinence and neurocognition: implications for cessation and relapse

FJ McClernon, MA Addicott, MM Sweitzer - The Neurobiology and …, 2015 - Springer
In this chapter, we review the last decade of research on the effects of smoking abstinence
on various forms of neurocognition, including executive function (working memory …

Blunted striatal response to monetary reward anticipation during smoking abstinence predicts lapse during a contingency-managed quit attempt

MM Sweitzer, CF Geier, R Denlinger, EE Forbes… - …, 2016 - Springer
Rationale Tobacco smoking is associated with dysregulated reward processing within the
striatum, characterized by hypersensitivity to smoking rewards and hyposensitivity to non …

[HTML][HTML] Imaging genetics and the neurobiological basis of individual differences in vulnerability to addiction

MM Sweitzer, EC Donny, AR Hariri - Drug and alcohol dependence, 2012 - Elsevier
BACKGROUND: Addictive disorders are heritable, but the search for candidate functional
polymorphisms playing an etiological role in addiction is hindered by complexity of the …

Impact of tobacco regulation on animal research: new perspectives and opportunities

EC Donny, TG Taylor, MG LeSage… - Nicotine & Tobacco …, 2012 - academic.oup.com
Abstract Introduction: The Family Smoking Prevention and Tobacco Control Act in the United
States and the World Health Organization Framework Convention on Tobacco or Health …

Reinforcement enhancing effects of nicotine via patch and nasal spray

KA Perkins, JL Karelitz, MC Boldry - Nicotine and Tobacco …, 2019 - academic.oup.com
Introduction Confirming preclinical findings, nicotine in humans (via smoking) enhances
reinforcement from nondrug rewards. Recent demonstration of similar effects with nicotine …

The effects of nicotine self-administration and withdrawal on concurrently available chow and sucrose intake in adult male rats

PE Bunney, D Burroughs, C Hernandez… - Physiology & …, 2016 - Elsevier
Carbohydrate intake, preference, and taste thresholds may be altered in current and former
cigarette smokers, which may mediate weight gain and risk for obesity in individuals who …