Estrogens and androgens in skeletal physiology and pathophysiology
Estrogens and androgens influence the growth and maintenance of the mammalian
skeleton and are responsible for its sexual dimorphism. Estrogen deficiency at menopause …
skeleton and are responsible for its sexual dimorphism. Estrogen deficiency at menopause …
Adverse effects of androgen deprivation therapy and strategies to mitigate them
PL Nguyen, SMH Alibhai, S Basaria, AV D'Amico… - European urology, 2015 - Elsevier
Context Androgen-deprivation therapy (ADT) is a key component of treatment for aggressive
and advanced prostate cancer, but it has also been associated with adverse effects on bone …
and advanced prostate cancer, but it has also been associated with adverse effects on bone …
EAU-ESTRO-SIOG guidelines on prostate cancer. Part II: treatment of relapsing, metastatic, and castration-resistant prostate cancer
Objective To present a summary of the 2016 version of the European Association of Urology
(EAU)–European Society for Radiotherapy & Oncology (ESTRO)–International Society of …
(EAU)–European Society for Radiotherapy & Oncology (ESTRO)–International Society of …
Sex steroid actions in male bone
Sex steroids are chief regulators of gender differences in the skeleton, and male gender is
one of the strongest protective factors against osteoporotic fractures. This advantage in bone …
one of the strongest protective factors against osteoporotic fractures. This advantage in bone …
Structural basis for antagonism and resistance of bicalutamide in prostate cancer
CE Bohl, W Gao, DD Miller, CE Bell… - Proceedings of the …, 2005 - National Acad Sciences
Carcinoma of the prostate is the most commonly diagnosed cancer in men. The current
pharmacological treatment of choice for progressive androgen-dependent prostate cancer is …
pharmacological treatment of choice for progressive androgen-dependent prostate cancer is …
Contemporary role of androgen deprivation therapy for prostate cancer
CONTEXT: Androgen deprivation therapy (ADT) for prostate cancer (PCa) represents one of
the most effective systemic palliative treatments known for solid tumors. Although clinical …
the most effective systemic palliative treatments known for solid tumors. Although clinical …
Medication-induced osteoporosis: screening and treatment strategies
K Panday, A Gona… - Therapeutic advances in …, 2014 - journals.sagepub.com
Drug-induced osteoporosis is a significant health problem and many physicians are
unaware that many commonly prescribed medications contribute to significant bone loss …
unaware that many commonly prescribed medications contribute to significant bone loss …
Aging and the male reproductive system
This narrative review presents an overview of current knowledge on fertility and reproductive
hormone changes in aging men, the factors driving and modulating these changes, their …
hormone changes in aging men, the factors driving and modulating these changes, their …
Drug-induced osteoporosis: mechanisms and clinical implications
Drug-induced osteoporosis is common and has a significant impact on the prognosis of
patients suffering from chronic debilitating diseases. Glucocorticoids are the drugs causing …
patients suffering from chronic debilitating diseases. Glucocorticoids are the drugs causing …
Expanded prostate cancer index composite for clinical practice: development and validation of a practical health related quality of life instrument for use in the routine …
P Chang, KM Szymanski, RL Dunn… - The Journal of …, 2011 - auajournals.org
Purpose: Measuring the health related quality of life of patients with prostate cancer in
routine clinical practice is hindered by the lack of instruments enabling efficient, real-time …
routine clinical practice is hindered by the lack of instruments enabling efficient, real-time …