Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders
A Annamneedi, C Gora, A Dudas… - British journal of …, 2023 - Wiley Online Library
Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two
core symptoms: deficits in social interaction and communication, and stereotyped …
core symptoms: deficits in social interaction and communication, and stereotyped …
Neuronal dopamine D3 receptors: translational implications for preclinical research and CNS disorders
B Kiss, I Laszlovszky, B Krámos, A Visegrády, A Bobok… - Biomolecules, 2021 - mdpi.com
Dopamine (DA), as one of the major neurotransmitters in the central nervous system (CNS)
and periphery, exerts its actions through five types of receptors which belong to two major …
and periphery, exerts its actions through five types of receptors which belong to two major …
Genetic basis of sleep bruxism and sleep apnea—response to a medical puzzle
Sleep bruxism (SB) and obstructive sleep apnea (OSA) are co-occurring sleep conditions.
The study aimed to evaluate the association of selected single-nucleotide polymorphisms …
The study aimed to evaluate the association of selected single-nucleotide polymorphisms …
Social cognition and schizophrenia: unresolved issues and new challenges in a maturing field of research
A Vaskinn, WP Horan - Schizophrenia bulletin, 2020 - academic.oup.com
Social cognition has become a topic of widespread interest in experimental and treatment
research in schizophrenia over the past 15 years. This explosion of interest largely reflects …
research in schizophrenia over the past 15 years. This explosion of interest largely reflects …
Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes
C Szpirer - Journal of biomedical science, 2020 - Springer
The laboratory rat has been used for a long time as the model of choice in several
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …
Binding of Dopamine D1 Receptor and Noradrenaline Transporter in Individuals with Autism Spectrum Disorder: A PET Study
Although previous studies have suggested the involvement of dopamine (DA) and
noradrenaline (NA) neurotransmissions in the autism spectrum disorder (ASD) …
noradrenaline (NA) neurotransmissions in the autism spectrum disorder (ASD) …
A Virtual In Vivo Dissection and Analysis of Socioaffective Symptoms Related to Cerebellum-Midbrain Reward Circuitry in Humans
LJ Hoffman, JM Foley, JK Leong… - Journal of …, 2024 - jneurosci.org
Emerging research in nonhuman animals implicates cerebellar projections to the ventral
tegmental area (VTA) in appetitive behaviors, but these circuits have not been characterized …
tegmental area (VTA) in appetitive behaviors, but these circuits have not been characterized …
Learning to recognize rat social behavior: Novel dataset and cross-dataset application
M Lorbach, EI Kyriakou, R Poppe, EA van Dam… - Journal of neuroscience …, 2018 - Elsevier
Background Social behavior is an important aspect of rodent models. Automated measuring
tools that make use of video analysis and machine learning are an increasingly attractive …
tools that make use of video analysis and machine learning are an increasingly attractive …
[HTML][HTML] Abnormal synaptic plasticity and impaired cognition in schizophrenia
XL Wu, QJ Yan, F Zhu - World journal of psychiatry, 2022 - ncbi.nlm.nih.gov
Schizophrenia (SCZ) is a severe mental illness that affects several brain domains with
relation to cognition and behaviour. SCZ symptoms are typically classified into three …
relation to cognition and behaviour. SCZ symptoms are typically classified into three …
A RATional choice for translational research?
T Aitman, P Dhillon, AM Geurts - Disease Models & …, 2016 - journals.biologists.com
Future prospects continue to be strong for research using the rat as a model organism. New
technology has enabled the proliferation of many new transgenic and knockout rat strains …
technology has enabled the proliferation of many new transgenic and knockout rat strains …