Obstructive sleep apnea (OSA) is a relatively common disease in the general population.
Besides its interaction with many comorbidities, it can also interact with potentially painful …

Pain serves as a vital innate defense mechanism that can significantly impact an individual's
quality of life. Understanding the physiological effects of pain well plays an important role in …

Chronic pain is a life-altering condition affecting millions of people. Current treatments are
inadequate and prolonged therapies come with severe side effects, especially dependence …

Pain is one of the most frequent and persistent side effects of breast cancer treatment.
Besides pain, breast cancer survivors (BCS) are prone to experience a myriad of other signs …

Central sensitisation is defined as a multifactorial etiopathogenetic condition involving an
increase in the reactivity of nociceptive neurons and alterations in pain transmission and …

Peripheral sensitization indicates increased responsiveness and reduced threshold of
nociceptive neurons in the periphery to the stimulation, which usually occurs after peripheral …

Objective The aim of this study was to quantify the temporal changes in inflammation and
TRPA1, TRPV1 and CGRP expression in the trigeminal ganglion during force-induced …

Numerous definitions of pain have been proposed over many years with different
implications when applied to clinical practice. This paper reviews information regarding the …

This article examines the involvement of the brain-derived neurotrophic factor (BDNF) in the
control of nociception and pain. BDNF, a neurotrophin known for its essential role in …

Pathological pain states arising from injuries to the nervous system are characterized by
sustained neuroinflammation and increased neuronal excitability at both peripheral and …