The discovery of a near-infrared (NIR, 650–900 nm) fluorescent chromophore hemicyanine
dye with high structural tailorability is of great significance in the field of detection …

Over the past decade, remarkable advances have been witnessed in the development of
small-molecule probes. These molecular tools have been widely applied for interrogating …

Optical imaging is crucial to study biological or pathological processes and diagnose
diseases. However, poor tissue penetration typically limits conventional optical imaging …

The activity levels of key substances (metal ions, reactive oxygen species, reactive nitrogen,
biological small molecules, etc.) in organisms are closely related to intracellular redox …

Fluorescence imaging utilizing traditional organic fluorophores is extensively applied in both
cellular and in vivo studies. However, it faces significant obstacles, such as low signal‐to …

Fluorophores with aggregation-induced emission (AIE) are characterized by many
advantageous features for biomedical applications, including excellent photostability and …

Molecular imaging is a non-invasive method to image and analyze the concentration and
activity of functional biomolecules in cells or in vivo at molecular level, and plays an …

Aminopeptidases are exopeptidases that catalyze the cleavage of amino acid residues from
the N‐terminal fragment of protein or peptide substrates. Owing to their function, they play …

In situ monitoring of the location and transportation of bioactive molecules is essential for
deciphering diverse biological events in the field of biomedicine. In addition, obtaining the in …

Many important biological species have been identified as cancer biomarkers and are
gradually becoming reliable targets for early diagnosis and late therapeutic evaluation of …