Current status of mannose receptor-targeted drug delivery for improved anti-HIV therapy
In the pursuit of achieving better therapeutic outcomes in the treatment of HIV, innovative
drug delivery strategies have been extensively explored. Mannose receptors, which are …
drug delivery strategies have been extensively explored. Mannose receptors, which are …
Novel nanotechnology-based approaches for targeting HIV reservoirs
Highly active anti-retroviral therapy (HAART) is prescribed for HIV infection and, to a certain
extent, limits the infection's spread. However, it cannot completely eradicate the latent virus …
extent, limits the infection's spread. However, it cannot completely eradicate the latent virus …
Mannose-anchored nano-selenium loaded nanostructured lipid carriers of etravirine for delivery to HIV reservoirs
The present investigation aims to develop and explore mannosylated lipid-based carriers to
deliver an anti-HIV drug, Etravirine (TMC) and Selenium nanoparticles (SeNPs), to the HIV …
deliver an anti-HIV drug, Etravirine (TMC) and Selenium nanoparticles (SeNPs), to the HIV …
A comprehensive review of nanosuspension loaded microneedles: fabrication methods, applications, and recent developments
Abstract Background Nanosuspension-loaded microneedles (MNs) are an emerging and
advanced strategy used extensively to formulate lipophilic molecules by embedding them …
advanced strategy used extensively to formulate lipophilic molecules by embedding them …
Tenofovir-tethered gold nanoparticles as a novel multifunctional long-acting anti-HIV therapy to overcome deficient drug delivery-: an in vivo proof of concept
Abstract Background The adoption of Antiretroviral Therapy (ART) substantially extends the
life expectancy and quality of HIV-infected patients. Yet, eliminating the latent reservoirs of …
life expectancy and quality of HIV-infected patients. Yet, eliminating the latent reservoirs of …
Dual loaded nanostructured lipid carrier of nano-selenium and Etravirine as a potential anti-HIV therapy
There is a dire need for dual-long-acting therapy that could simultaneously target different
stages of the HIV life cycle and providing a dual-prolonged strategy for improved anti-HIV …
stages of the HIV life cycle and providing a dual-prolonged strategy for improved anti-HIV …
Cutting-edge advances in nanocarrier-facilitated topical drug delivery systems for targeted skin cancer therapy: A comprehensive review
Skin cancer is one of the most common and complex types of the disease, resulting in a high
mortality rate worldwide. Skin cancer can be treated with chemotherapy, surgery …
mortality rate worldwide. Skin cancer can be treated with chemotherapy, surgery …
Exploring modified chitosan-based gene delivery technologies for therapeutic advancements
One of the critical steps in gene therapy is the successful delivery of the genes.
Immunogenicity and toxicity are major issues for viral gene delivery systems. Thus, non-viral …
Immunogenicity and toxicity are major issues for viral gene delivery systems. Thus, non-viral …
Biocompatible metal–organic frameworks as promising platforms to eradicate HIV reservoirs ex vivo in people living with HIV
The HIV attacks the immune system provoking an infection that is considered a global health
challenge. Despite antiretroviral treatments being effective in reducing the plasma viral load …
challenge. Despite antiretroviral treatments being effective in reducing the plasma viral load …
Revolutionizing Antiviral Therapeutics: Unveiling Innovative Approaches for Enhanced Drug Efficacy
Since the beginning of the coronavirus pandemic in late 2019, viral infections have become
one of the top three causes of mortality worldwide. Immunization and the use of …
one of the top three causes of mortality worldwide. Immunization and the use of …