The serum-and glucocorticoid-inducible kinase-1 (SGK1) is ubiquitously expressed and
under genomic control by cell stress (including cell shrinkage) and hormones (including …

Diabetes mellitus contributes greatly to morbidity, mortality, and overall health care costs. In
major part, these outcomes derive from the high incidence of progressive kidney dysfunction …

Mutations in the gene encoding for the Na+-glucose co-transporter SGLT2 (SLC5A2)
associate with familial renal glucosuria, but the role of SGLT2 in the kidney is incompletely …

Inflammation has emerged as a critical biological process contributing to hypertensive
cardiac remodeling. Effective pharmacological treatments targeting the cardiac inflammatory …

Inflammation plays a central role in the development of heart failure, especially in heart
failure with preserved ejection fraction (HFpEF). Furthermore, the inflammatory response …

Background—Mineralocorticoid receptor (MR) blockade improves morbidity and mortality
among patients with heart failure; however, the underlying mechanisms are still under …

The ubiquitously expressed serum‐and glucocorticoid‐inducible kinase‐1 (SGK1) is
genomically regulated by cell stress (including cell shrinkage) and several hormones …

Cardiac fibrosis is a major pathogenic factor in a variety of cardiovascular diseases and
refers to an excessive deposition of extracellular matrix components in the heart, which …

Diuretics acting on the distal renal tubule for preterm infants with (or develo**) chronic lung
disease - Stewart, A - 2011 | Cochrane Library Skip to Content Cookies Our site uses cookies …

Objective—Inflammatory responses play a pivotal role in the pathogenesis of hypertensive
cardiac remodeling. Macrophage recruitment and polarization contribute to the development …