Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …

Over the last decade, the nanomedicine has experienced unprecedented development in
diagnosis and management of diseases. A number of nanomedicines have been approved …

Artificial intelligence (AI) and nanotechnology are two fields that are instrumental in realizing
the goal of precision medicine—tailoring the best treatment for each cancer patient. Recent …

Obtaining efficient drug delivery to the brain remains the biggest challenge for the
development of therapeutics to treat diseases of the central nervous system. The main …

Vascular endothelium offers a variety of therapeutic targets for the treatment of cancer,
cardiovascular diseases, inflammation, and oxidative stress. Significant research has been …

Nanoparticles have shown promise as both drug delivery vehicles and direct antitumor
systems, but they must be properly designed in order to maximize efficacy. Computational …

It is generally accepted that the presentation of multiple ligands on a nanoparticle (NP)
surface can improve cell targeting; however, little work has been done to determine whether …

Nanoparticles modified with ligands for specific targeting towards receptors expressed on
the surface of target cells are discussed in literature towards improved delivery strategies. In …

Receptor‐mediated drug delivery presents an opportunity to enhance therapeutic efficiency
by accumulating drug within the tissue of interest and reducing undesired, off‐target effects …

Using coarse-grained molecular dynamics simulations, we systematically investigate the
receptor-mediated endocytosis of elastic nanoparticles (NPs) with different sizes, ranging …