The Implementation of the Biopsychosocial Model: Individuals With Alcohol Use Disorder and Post‐Traumatic Stress Disorder

F Hinostroza, MM Mahr - Brain and Behavior, 2025 - Wiley Online Library
Introduction This extensive literature review investigates the relationship between post‐
traumatic stress disorder (PTSD) and alcohol use disorder (AUD), focusing on the …

Epigallocatechin-gallate attenuates rapamycin exacerbated high fat diet-induced autophagy, hormonal dysregulation, testicular and brain oxidative stress, and …

CC Onyekweli, B Ben-Azu, OM Oyovwi… - Food and Chemical …, 2024 - Elsevier
This study investigated whether epigallocatechin-gallate (EGCG) could counteract the
detrimental effects of high-fat diet (HFD)-induced obesity in rats exposed to rapamycin …

Psychopharmacological interaction of alcohol and posttraumatic stress disorder: Effective action of naringin

B Ben-Azu, B Oritsemuelebi, AM Oghorodi… - European Journal of …, 2024 - Elsevier
Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) are prevalently co-
occurring, important risk factors for a broad array of neuropsychiatric diseases. To date, how …

Carvacrol alleviates CUMS-induced depressive-like behaviors and cognitive impairment by reducing oxidative stress and neuroinflammation in mice

JT Valentim, DMA da Silva, VCC Capibaribe… - Behavioural Brain …, 2024 - Elsevier
The present study aimed to evaluate the protective potential of carvacrol against depressive-
like behavior and cognitive impairment prompted by chronic unpredictable mild stress …

A chloro substituted organoselenium mitigates stress-associated memory impairment and hippocampal glutamatergic function in a repeated Forced Swim Stress …

VA Zborowski, CC Martins, LS Marques, SO Heck… - Neuroscience, 2024 - Elsevier
Stress is triggered by a threatening event that alters the regulation of emotion, behavior, and
cognition. The effects of stress on memory in animal models are well-documented. Firstly …

Alcohol exacerbates post-traumatic stress psychiatric behavior and its neuropathological sequalae in experimental mice: preventive effects of morin

B Ben-Azu, PEY Toloyai, A Adebesin, VO Ojiokor… - Alcohol, 2025 - Elsevier
Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) are very prevalent and
co-occurring. It is unclear how alcohol exacerbates PTSD predicaments owing to less …

[HTML][HTML] Geraniol mitigates anxiety-like behaviors in rats by reducing oxidative stress, repairing impaired hippocampal neurotransmission, and normalizing brain …

R Nisar, A Inamullah, AUF Ghalib, H Nisar… - Biomedicine & …, 2024 - Elsevier
Anxiety-like conditions can interfere with daily activities as the adaptive mechanism fails to
cope with stress. These conditions are often linked with increased oxidative stress, and …

Alcohol exacerbates psychosocial stress-induced neuropsychiatric symptoms: Attenuation by geraniol

B Ben-Azu, A Adebesin, GE Moke, VO Ojiokor… - Neurochemistry …, 2024 - Elsevier
Adaptation to psychosocial stress is psychologically distressing, initiating/promoting
comorbidity with alcohol use disorders. Emerging evidence moreover showed that ethanol …

Geraniol Ameliorates Pentylenetetrazol-Induced Epilepsy, Neuroinflammation, and Oxidative Stress via Modulating the GABAergic Tract: In vitro and in vivo studies

NS Younis, MM Almostafa… - … Design, Development and …, 2024 - Taylor & Francis
Introduction Geraniol (Ger), a monoterpene, is a common constituent of several essential
oils. This study explored the anticonvulsant effect of Ger in-vitro using nerve growth factor …

Taurine, an essential amino acid, attenuates rotenone-induced Parkinson's disease in rats by inhibiting alpha-synuclein aggregation and augmenting dopamine …

JE Onuelu, B Ben-Azu, OG Adebayo, AR Fokoua… - Behavioural Brain …, 2025 - Elsevier
Reducing antioxidant levels exacerbates the generation of reactive oxygen/nitrogen
species, leading to alpha-synuclein aggregation and the degeneration of dopaminergic …