TRP channels role in pain associated with neurodegenerative diseases
M Duitama, V Vargas-López, Z Casas… - Frontiers in …, 2020 - frontiersin.org
Transient receptor potential (TRP) are cation channels expressed in both non-excitable and
excitable cells from diverse tissues, including heart, lung, and brain. The TRP channel family …
excitable cells from diverse tissues, including heart, lung, and brain. The TRP channel family …
[HTML][HTML] Role of kinase-coupled TRP channels in mineral homeostasis
Transient receptor potential (TRP) proteins TRPM6 and TRPM7 are α-kinase-coupled
divalent cation-selective channels activated upon a reduction of cytosolic levels of Mg 2+ …
divalent cation-selective channels activated upon a reduction of cytosolic levels of Mg 2+ …
TRP Channels in the Heart
M Freichel, M Berlin, A Schürger, I Mathar… - Neurobiology of TRP …, 2017 - books.google.com
Calcium is an important second messenger in cardiac function. It is not only critical for the
excitationcontraction coupling and relaxation of the heart (Bers, 2002), but it is also …
excitationcontraction coupling and relaxation of the heart (Bers, 2002), but it is also …
How the kidney regulates magnesium: a modelling study
The kidneys are crucial for maintaining Mg2+ homeostasis. Along the proximal tubule and
thick ascending limb, Mg2+ is reabsorbed paracellularly, while along the distal convoluted …
thick ascending limb, Mg2+ is reabsorbed paracellularly, while along the distal convoluted …
Dexamethasone and sex regulate placental glucocorticoid receptor isoforms in mice
Maternal dexamethasone exposure in the mouse impairs placental development and
programs adult disease in a sexually dimorphic manner. Glucocorticoids bind to different …
programs adult disease in a sexually dimorphic manner. Glucocorticoids bind to different …
Placental adaptations to micronutrient dysregulation in the programming of chronic disease
Poor nutrition during pregnancy is known to impair foetal development and increase the risk
of chronic disease in offspring. Both macronutrients and micronutrients are required for a …
of chronic disease in offspring. Both macronutrients and micronutrients are required for a …
Placental O-GlcNAc-transferase expression and interactions with the glucocorticoid receptor are sex specific and regulated by maternal corticosterone exposure in …
M Pantaleon, SE Steane, K McMahon, JSM Cuffe… - Scientific Reports, 2017 - nature.com
Maternal stress programs offspring disease in a sexually dimorphic manner with males often
more adversely affected. Previous studies of maternal glucocorticoid exposure suggest male …
more adversely affected. Previous studies of maternal glucocorticoid exposure suggest male …
Immunomodulatory functions of TRPM7 and its implications in autoimmune diseases
HY Liang, Y Chen, X Wei, GG Ma, J Ding, C Lu… - …, 2022 - Wiley Online Library
An autoimmune disease is an inappropriate response to one's tissues due to a break in
immune tolerance and exposure to self‐antigens. It often leads to structural and functional …
immune tolerance and exposure to self‐antigens. It often leads to structural and functional …
TRPM7 and MagT1 in the osteogenic differentiation of human mesenchymal stem cells in vitro
S Castiglioni, V Romeo, L Locatelli, A Cazzaniga… - Scientific Reports, 2018 - nature.com
Mesenchymal stem cells are fundamental for bone formation and repair since they respond
to microenvironmental stimuli by undergoing osteogenic differentiation. We show that the …
to microenvironmental stimuli by undergoing osteogenic differentiation. We show that the …
[HTML][HTML] Beyond ion-conduction: Channel-dependent and-independent roles of TRP channels during development and tissue homeostasis
Transient receptor potential (TRP) channels comprise a family of cation channels implicated
in a variety of cellular processes, including proliferation, cell migration and cell survival. As a …
in a variety of cellular processes, including proliferation, cell migration and cell survival. As a …