Coupling mechanism and significance of the BOLD signal: a status report

EMC Hillman - Annual review of neuroscience, 2014 - annualreviews.org
Functional magnetic resonance imaging (fMRI) provides a unique view of the working
human mind. The blood-oxygen-level-dependent (BOLD) signal, detected in fMRI, reflects …

Wide-field optical map** of neural activity and brain haemodynamics: considerations and novel approaches

Y Ma, MA Shaik, SH Kim… - … of the Royal …, 2016 - royalsocietypublishing.org
Although modern techniques such as two-photon microscopy can now provide cellular-level
three-dimensional imaging of the intact living brain, the speed and fields of view of these …

Optical brain imaging in vivo: techniques<?xpp qa?> and applications from animal to man

EMC Hillman - Journal of biomedical optics, 2007 - spiedigitallibrary.org
Optical brain imaging has seen 30 years of intense development, and has grown into a rich
and diverse field. In-vivo imaging using light provides unprecedented sensitivity to functional …

How and when the fMRI BOLD signal relates to underlying neural activity: the danger in dissociation

A Ekstrom - Brain research reviews, 2010 - Elsevier
Functional magnetic resonance imaging (fMRI) has become the dominant means of
measuring behavior-related neural activity in the human brain. Yet the relation between the …

Does the brain have a baseline? Why we should be resisting a rest

AM Morcom, PC Fletcher - Neuroimage, 2007 - Elsevier
In the last few years, the notion that the brain has a default or intrinsic mode of functioning
has received increasing attention. The idea derives from observations that a consistent …

Neurovascular coupling in normal aging: a combined optical, ERP and fMRI study

M Fabiani, BA Gordon, EL Maclin, MA Pearson… - Neuroimage, 2014 - Elsevier
Brain aging is characterized by changes in both hemodynamic and neuronal responses,
which may be influenced by the cardiorespiratory fitness of the individual. To investigate the …

Functional connectivity of the brain across rodents and humans

N Xu, TJ LaGrow, N Anumba, A Lee, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Resting-state functional magnetic resonance imaging (rs-fMRI), which measures the
spontaneous fluctuations in the blood oxygen level-dependent (BOLD) signal, is …

Investigating human neurovascular coupling using functional neuroimaging: a critical review of dynamic models

C Huneau, H Benali, H Chabriat - Frontiers in neuroscience, 2015 - frontiersin.org
The mechanisms that link a transient neural activity to the corresponding increase of
cerebral blood flow (CBF) are termed neurovascular coupling (NVC). They are possibly …

Depth-resolved optical imaging and microscopy of vascular compartment dynamics during somatosensory stimulation

EMC Hillman, A Devor, MB Bouchard, AK Dunn… - Neuroimage, 2007 - Elsevier
The cortical hemodynamic response to somatosensory stimulus is investigated at the level of
individual vascular compartments using both depth-resolved optical imaging and in-vivo two …

Electrophysiological correlates of the BOLD signal for EEG‐informed fMRI

T Murta, M Leite, DW Carmichael… - Human brain …, 2015 - Wiley Online Library
Electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) are
important tools in cognitive and clinical neuroscience. Combined EEG–fMRI has been …