[HTML][HTML] Bacterial stress responses as potential targets in overcoming antibiotic resistance

J Dawan, J Ahn - Microorganisms, 2022 - mdpi.com
Bacteria can be adapted to adverse and detrimental conditions that induce general and
specific responses to DNA damage as well as acid, heat, cold, starvation, oxidative …

Molecular mechanisms of two-component signal transduction

CP Zschiedrich, V Keidel, H Szurmant - Journal of molecular biology, 2016 - Elsevier
Two-component systems (TCS) comprising sensor histidine kinases and response regulator
proteins are among the most important players in bacterial and archaeal signal transduction …

Roux-en-Y gastric bypass and vertical banded gastroplasty induce long-term changes on the human gut microbiome contributing to fat mass regulation

V Tremaroli, F Karlsson, M Werling, M Ståhlman… - Cell metabolism, 2015 - cell.com
Bariatric surgery is currently the most effective procedure for the treatment of obesity. Given
the role of the gut microbiota in regulating host metabolism and adiposity, we investigated …

A c-di-GMP signaling module controls responses to iron in Pseudomonas aeruginosa

X Zhan, K Zhang, C Wang, Q Fan, X Tang… - Nature …, 2024 - nature.com
Cyclic dimeric guanosine monophosphate (c-di-GMP) serves as a bacterial second
messenger that modulates various processes including biofilm formation, motility, and host …

Structural insights into the signalling mechanisms of two-component systems

F Jacob-Dubuisson, A Mechaly, JM Betton… - Nature Reviews …, 2018 - nature.com
Two-component systems reprogramme diverse aspects of microbial physiology in response
to environmental cues. Canonical systems are composed of a transmembrane sensor …

Mucins and their role in sha** the functions of mucus barriers

CE Wagner, KM Wheeler… - Annual review of cell and …, 2018 - annualreviews.org
We review what is currently understood about how the structure of the primary solid
component of mucus, the glycoprotein mucin, gives rise to the mechanical and biochemical …

[HTML][HTML] Enterococcal infection—treatment and antibiotic resistance

CJ Kristich, LB Rice, CA Arias - 2014 - europepmc.org
The clinical importance of the genus Enterococcus is directly related to its antibiotic
resistance, which contributes to the risk of colonization and infection. The species of the …

Recognition and degradation of plant cell wall polysaccharides by two human gut symbionts

EC Martens, EC Lowe, H Chiang, NA Pudlo, M Wu… - PLoS …, 2011 - journals.plos.org
Symbiotic bacteria inhabiting the human gut have evolved under intense pressure to utilize
complex carbohydrates, primarily plant cell wall glycans in our diets. These polysaccharides …

A catalogue of signal molecules that interact with sensor kinases, chemoreceptors and transcriptional regulators

MA Matilla, F Velando, D Martín-Mora… - FEMS Microbiology …, 2022 - academic.oup.com
Bacteria have evolved many different signal transduction systems that sense signals and
generate a variety of responses. Generally, most abundant are transcriptional regulators …

The ArcAB two-component system: function in metabolism, redox control, and infection

AN Brown, MT Anderson, MA Bachman… - Microbiology and …, 2022 - journals.asm.org
ArcAB, also known as the Arc system, is a member of the two-component system family of
bacterial transcriptional regulators and is composed of sensor kinase ArcB and response …