Agnostic approvals in oncology: getting the right drug to the right patient with the right genomics
V Tateo, PV Marchese, V Mollica, F Massari… - Pharmaceuticals, 2023 - mdpi.com
(1) Background: The oncology field has drastically changed with the advent of precision
medicine, led by the discovery of druggable genes or immune targets assessed through next …
medicine, led by the discovery of druggable genes or immune targets assessed through next …
Recent advances in drug delivery and targeting for the treatment of pancreatic cancer
Despite significant treatment efforts, pancreatic ductal adenocarcinoma (PDAC), the
deadliest solid tumor, is still incurable in the preclinical stages due to multifacet stroma …
deadliest solid tumor, is still incurable in the preclinical stages due to multifacet stroma …
Antibacterial potential of trihydroxycyclohexa-2, 4-diene-1-carboxylic acid: Insight from DFT, molecular docking, and molecular dynamic simulation
Abstract In this study,(z)-5-((3-(2, 3-dihydroxyphenyl) acryloyl) oxy)-1, 3, 4-
trihydroxycyclohexa-2, 4-diene-1-carboxylic acid (chlorogenic acid) was isolated and …
trihydroxycyclohexa-2, 4-diene-1-carboxylic acid (chlorogenic acid) was isolated and …
[HTML][HTML] Comprehensive review on endoscopic ultrasound-guided tissue acquisition techniques for solid pancreatic tumor
S Masuda, K Koizumi, K Shionoya… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma is speculated to become the second leading cause of
cancer-related mortality by 2030, a high mortality rate considering the number of cases …
cancer-related mortality by 2030, a high mortality rate considering the number of cases …
Complete response to alectinib in ALK-fusion metastatic salivary ductal carcinoma
The advent of next-generation sequencing (NGS) has allowed for the identification of novel
therapeutic targets for patients with uncommon cancers. It is well known that fusion …
therapeutic targets for patients with uncommon cancers. It is well known that fusion …
Understanding the Genetic Landscape of Pancreatic Ductal Adenocarcinoma to Support Personalized Medicine: A Systematic Review
A Pantaleo, G Forte, C Fasano, M Lepore Signorile… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with
high mortality. Most patients present with an advanced stage of the disease, highlighting the …
high mortality. Most patients present with an advanced stage of the disease, highlighting the …
[HTML][HTML] Multimodal machine learning models identify chemotherapy drugs with prospective clinical efficacy in dogs with relapsed B-cell lymphoma
AJ Callegari, J Tsang, S Park, D Swartzfager… - Frontiers in …, 2024 - frontiersin.org
Dogs with B-cell lymphoma typically respond well to first-line CHOP-based chemotherapy,
but there is no standard of care for relapsed patients. To help veterinary oncologists select …
but there is no standard of care for relapsed patients. To help veterinary oncologists select …
Exosomes: Emerging Modulators of Pancreatic Cancer Drug Resistance
M Di Donato, N Medici, A Migliaccio, G Castoria… - Cancers, 2023 - mdpi.com
Simple Summary The high mortality of pancreatic cancer (PaC) is due to different reasons: a
lack of specific symptoms, an unlikely diagnosis, therapies' paucity, and drug resistance …
lack of specific symptoms, an unlikely diagnosis, therapies' paucity, and drug resistance …
Exploring the Potential of Compounds Isolated from Laranthus micranthus for the Treatment of Benign Prostatic Hyperplasia: Comprehensive Studies on …
RU Ukpanukpong, AE Azubuike, EI Agwupuye… - Chemistry Africa, 2024 - Springer
Owing to the significant challenges encountered in the diagnosis, management, and
treatment of benign prostatic hyperplasia (BPH), which have emerged as essential clinical …
treatment of benign prostatic hyperplasia (BPH), which have emerged as essential clinical …
Exceptional response to MEK inhibition in a patient with RAF1-mutant myxofibrosarcoma: case report and mechanistic overview
Exceptional Response to MEK Inhibition in a Patient With RAF1-Mutant Myxofibrosarcoma: Case
Report and Mechanistic Overview | JCO Precision Oncology Skip to main content ASCO …
Report and Mechanistic Overview | JCO Precision Oncology Skip to main content ASCO …