[HTML][HTML] Treatment of human babesiosis: then and now

I Renard, C Ben Mamoun - Pathogens, 2021 - mdpi.com
Babesiosis is an emerging tick-borne disease caused by apicomplexan parasites of the
genus Babesia. With its increasing incidence worldwide and the risk of human-to-human …

[HTML][HTML] A Comprehensive Insight on the Health Benefits and Phytoconstituents of Camellia sinensis and Recent Approaches for Its Quality Control

MM Aboulwafa, FS Youssef, HA Gad, AE Altyar… - Antioxidants, 2019 - mdpi.com
Tea, Camellia sinensis, which belongs to the family Theaceae, is a shrub or evergreen tree
up to 16 m in height. Green tea is very popular because of its marked health benefits …

Pyronaridine: An update of its pharmacological activities and mechanisms of action

C Bailly - Biopolymers, 2021 - Wiley Online Library
Pyronaridine (PYR) is an erythrocytic schizonticide with a potent antimalarial activity against
multidrug‐resistant Plasmodium. The drug is used in combination with artesunate for the …

Inhibitory effects of fluoroquinolone antibiotics on Babesia divergens and Babesia microti, blood parasites of veterinary and zoonotic importance

MA Rizk, M AbouLaila, SAES El-Sayed… - Infection and Drug …, 2018 - Taylor & Francis
Aim: This study aimed to evaluate the inhibitory effects of fluoroquinolone antibiotics,
including enrofloxacin, enoxacin, trovafloxacin, norfloxacin, and ofloxacin, on the in vitro and …

Evaluation of the in vitro and in vivo inhibitory effect of thymoquinone on piroplasm parasites

SAES El-Sayed, MA Rizk, N Yokoyama, I Igarashi - Parasites & vectors, 2019 - Springer
Background Develo** new antibabesial drugs with a low toxic effect to the animal and
with no resistance from Babesia parasites is in urgent demand. In this concern, the …

[HTML][HTML] Diminazene aceturate and imidocarb dipropionate-based combination therapy for babesiosis–a new paradigm

MA Rizk, SAES El-Sayed, I Igarashi - Ticks and tick-borne diseases, 2023 - Elsevier
In the present study, the effect of a combination therapy consisting of diminazene aceturate
(DA) and imidocarb dipropionate (ID) on the in vitro growth of several parasitic piroplasmids …

Discovering the in vitro potent inhibitors against Babesia and Theileria parasites by repurposing the Malaria Box: A review

MA Rizk, SAES El-Sayed, S El-Khodery… - Veterinary …, 2019 - Elsevier
There is an innovative approach to discovering and develo** novel potent and safe anti-
Babesia and anti-Theileria agents for the control of animal piroplasmosis. Large-scale …

Assay methods for in vitro and in vivo anti-Babesia drug efficacy testing: Current progress, outlook, and challenges

MA Rizk, SAES El-Sayed, M Nassif, J Mosqueda… - Veterinary …, 2020 - Elsevier
Absence of an effective high-throughput drug-screening system for Babesia parasites is
considered one of the main causes for the presence of a wide gap in the treatment of animal …

Evaluation of the inhibitory effect of N-acetyl-L-cysteine on Babesia and Theileria parasites

MA Rizk, SAES El-Sayed, M AbouLaila… - Experimental …, 2017 - Elsevier
N-acetyl-L-cysteine is known to have antibacterial, antiviral, antimalarial, and antioxidant
activities. Therefore, the in vitro inhibitory effect of this hit was evaluated in the present study …

Myrrh Oil in Vitro Inhibitory Growth on Bovine and Equine Piroplasm Parasites and Babesia microti of Mice

M AbouLaila, SAES El-Sayed, MA Omar… - Pathogens, 2020 - mdpi.com
The present experimental study was conducted for the assessment of the efficacy of in vitro
inhibition of myrrh oil on the propagation of Babesia bovis, B. divergens, B. bigemina …