The role of liver sinusoidal endothelial cells in metabolic dysfunction-associated steatotic liver diseases and liver cancer: mechanisms and potential therapies

H Mo, P Yue, Q Li, Y Tan, X Yan, X Liu, Y Xu, Y Luo… - Angiogenesis, 2025 - Springer
Liver sinusoidal endothelial cells (LSECs), with their unique morphology and function, have
garnered increasing attention in chronic liver disease research. This review summarizes the …

Designing biomaterials for the treatment of autoimmune diseases

B Tang, X **e, J Lu, W Huang, J Yang, J Tian… - Applied Materials …, 2024 - Elsevier
Autoimmune diseases (ADs) are a group of chronic relapsing inflammatory diseases that
cause great suffering to patients and increase the economic burden of society. However, the …

Nanoparticles loaded with IL-2 and TGF-β promote transplantation tolerance to alloantigen

DA Horwitz, JH Wang, D Kim, C Kang, K Brion… - Frontiers in …, 2024 - frontiersin.org
We have previously reported that nanoparticles (NPs) loaded with IL-2 and TGF-β and
targeted to T cells induced polyclonal T regulatory cells (Tregs) that protected mice from graft …

Optimized strategies for precise messenger RNA delivery using site-specific lipid nanoparticle-based drug delivery systems

W Cao, T **a - Nanomedicine, 2025 - Taylor & Francis
Lipid nanoparticles (LNPs) have become the delivery of choice for nanomedicines. LNPs
offer the necessary efficacy and production efficiency for a new generation of therapeutics …

Liver-targeting iron oxide nanoparticles and their complexes with plant extracts for biocompatibility

SA Kazaryan, SA Oganian… - Beilstein Journal of …, 2024 - beilstein-journals.org
Thanks to their simple synthesis, controlled physical properties, and minimal toxicity, iron
oxide nanoparticles (Fe 3 O 4 NPs) are widely used in many biomedical applications (eg …

[HTML][HTML] Radiolabelled Nanomaterials for Diagnostic and Therapeutic Applications in Hepatocellular Carcinoma and Other Liver Diseases

J Fu, L Chen, J Hu, C Yu, J Yin - Precision Medicine and Engineering, 2025 - Elsevier
Nuclear medicine plays a pivotal role in diagnosing and treating liver diseases such as
hepatocellular carcinoma (HCC), fibrosis, and non-alcoholic steatohepatitis. Positron …

[HTML][HTML] Formulation Development, Optimization and Evaluation of Imipramine Loaded Nano-Structured Lipid Carrier

R Roy, V Sankar, P Ragavendra - Journal of Young Pharmacists, 2024 - jyoungpharm.org
Background Nano-structure Lipid Carriers (NLCs) are small spheres extending in scale from
10 to 1000 nanometres comprised of biocompatible and biodegradable lipids. These …