Bronchiectasis exacerbation: a narrative review of causes, risk factors, management and prevention

H Choi, JD Chalmers - Annals of Translational Medicine, 2022 - pmc.ncbi.nlm.nih.gov
Background and Objective Bronchiectasis exacerbations are significant events in the natural
course of the disease and determine long-term clinical outcomes. This review aims to …

[Translated article] Biological Biomarkers in Respiratory Diseases

F García-Río, B Alcázar-Navarrete… - Archivos de …, 2022 - Elsevier
In recent years, personalized or precision medicine has made effective inroads into the
management of diseases, including respiratory diseases. The route to implementing this …

C-reactive protein: pathophysiology, diagnosis, false test results and a novel diagnostic algorithm for clinicians

DS Mouliou - Diseases, 2023 - mdpi.com
The current literature provides a body of evidence on C-Reactive Protein (CRP) and its
potential role in inflammation. However, most pieces of evidence are sparse and …

Inhaled corticosteroids in adults with non-cystic fibrosis bronchiectasis: from bench to bedside. A narrative review

MÁ Martínez-García, G Oscullo, A García-Ortega… - Drugs, 2022 - Springer
Due to their potent anti-inflammatory capacity (particularly in predominantly eosinophilic
inflammation) and immunosuppressive properties, inhaled corticosteroids (ICSs) are widely …

Biomarkers in bronchiectasis

E Johnson, MB Long… - European Respiratory …, 2024 - publications.ersnet.org
Bronchiectasis is a heterogeneous disease with multiple aetiologies and diverse clinical
features. There is a general consensus that optimal treatment requires precision medicine …

[HTML][HTML] Endotypes in bronchiectasis: moving towards precision medicine. A narrative review

M Martins, HR Keir, JD Chalmers - Pulmonology, 2023 - Elsevier
Bronchiectasis is a highly complex entity that can be very challenging to investigate and
manage. Patients are diverse in their aetiology, symptoms, risk of complications and …

Pathophysiology of chronic bronchial infection in bronchiectasis

B Solarat, L Perea, R Faner, D de La Rosa… - Archivos de …, 2023 - Elsevier
Bronchiectasis is a complex and heterogeneous disease. Its pathophysiology is poorly
understood, but chronic bronchial infection plays an important role in its natural history, and …

Significance and potential role of eosinophils in non-cystic fibrosis bronchiectasis

W Guan, G Oscullo, M He, D Xu… - The Journal of Allergy …, 2023 - Elsevier
Bronchiectasis is a complex and heterogeneous disease with a myriad of pulmonary and
extrapulmonary etiologies. Bronchiectasis has a predominantly neutrophilic inflammatory …

The U-shaped relationship between eosinophil count and bronchiectasis severity: the effect of inhaled corticosteroids

MÁ Martínez-García, R Méndez, C Olveira, R Girón… - Chest, 2023 - Elsevier
Background Although a proven relationship exists between the blood eosinophil count
(BEC) and the severity of both asthma and COPD, its relationship with bronchiectasis has …

Phenotypic clustering in non-cystic fibrosis bronchiectasis patients: the role of eosinophils in disease severity

X Wang, C Villa, Y Dobarganes, C Olveira… - International journal of …, 2021 - mdpi.com
Whether high blood eosinophil counts may define a better phenotype in bronchiectasis
patients, as shown in chronic obstructive pulmonary disease (COPD), remains to be …