Drug delivery for tumor theranostics involves the extensive use of the enhanced permeability
and retention (EPR) effect. Previously, various types of nanomedicines have been …

Ultrasound (US) medical technology is widely used due to its advantages of safety, speed,
and low cost. With the rapid development of biomedical nanotechnology …

Hypoxia not only promotes tumor metastasis but also strengthens tumor resistance to
therapies that demand the involvement of oxygen, such as radiation therapy and …

Photodynamic therapy (PDT) typically involves oxygen (O2) consumption and therefore
suffers from greatly limited anticancer therapeutic efficacy in tumor hypoxia. Here, it is …

After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …

Administration of drugs through oral and intravenous routes is a mainstay of modern
medicine, but this approach suffers from limitations associated with off-target side effects and …

Tissue engineering (TE) has provided promising strategies for regenerating tissue defects,
but few TE approaches have been translated for clinical applications. One major barrier in …

Tumor microenvironments (TMEs) have received increasing attention in recent years as they
play pivotal roles in tumorigenesis, progression, metastases, and resistance to the traditional …

Tumor hypoxia is believed to be a factor limiting successful outcomes of oxygen-consuming
cancer therapy, thereby reducing patient survival. A key strategy to overcome tumor hypoxia …

Manufacturing macroscale cell-laden architectures is one of the biggest challenges faced
nowadays in the domain of tissue engineering. Such living constructs, in fact, pose strict …