Metabolic control of innate lymphoid cells in health and disease

L Zhou, Q Lin, GF Sonnenberg - Nature metabolism, 2022 - nature.com
Innate lymphoid cells (ILCs) are a family of predominantly tissue-resident lymphocytes that
critically orchestrate immunity, inflammation, tolerance and repair at barrier surfaces of the …

[HTML][HTML] Innate lymphoid cell plasticity in mucosal infections

AA Korchagina, E Koroleva, AV Tumanov - Microorganisms, 2023 - mdpi.com
Mucosal tissue homeostasis is a dynamic process that involves multiple mechanisms
including regulation of innate lymphoid cells (ILCs). ILCs are mostly tissue-resident cells …

[HTML][HTML] Dietary butyrate, lauric acid and stearic acid improve gut morphology and epithelial cell turnover in weaned piglets

X Zeng, Y Yang, J Wang, Z Wang, J Li, Y Yin, H Yang - Animal Nutrition, 2022 - Elsevier
This study was to evaluate the effects of the supplementation of saturated fatty acids with
different chain lengths on growth performance, intestinal morphology, epithelial cell …

mTORC2 acts as a gatekeeper for mTORC1 deficiency-mediated impairments in ILC3 development

Y Deng, S Wu, H Peng, L Tian, Y Li, Y Yang… - Acta Pharmacologica …, 2023 - nature.com
Group 3 innate lymphoid cells (ILC3s) are mediators of intestinal immunity and barrier
function. Recent studies have investigated the role of the mammalian target of rapamycin …

Hyperbaric oxygen augments susceptibility to C. difficile infection by impairing gut microbiota ability to stimulate the HIF-1α-IL-22 axis in ILC3

JL Fachi, LP Pral, HC Assis, S Oliveira… - Gut …, 2024 - Taylor & Francis
Hyperbaric oxygen (HBO) therapy is a well-established method for improving tissue
oxygenation and is typically used for the treatment of various inflammatory conditions …

Role of innate lymphoid cells in obesity and insulin resistance

H Chen, L Sun, L Feng, Y Yin, W Zhang - Frontiers in Endocrinology, 2022 - frontiersin.org
Obesity, a growing chronic metabolic disease, greatly increases the risk of metabolic
syndrome which includes type 2 diabetes, fatty liver and cardiovascular diseases. Obesity …

[HTML][HTML] IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis

A Valle-Noguera, L Sancho-Temiño… - Cell Reports, 2023 - cell.com
Group 3 innate lymphoid cells (ILC3s) are vital for defending tissue barriers from invading
pathogens. Hypoxia influences the production of intestinal ILC3-derived cytokines by …

[HTML][HTML] Bcl-2 supports survival and metabolic fitness of quiescent tissue-resident ILC3

JI King, F Melo-Gonzalez, B Malengier-Devlies… - Mucosal …, 2023 - Elsevier
Group 3 innate lymphoid cells (ILC3) are potent effector cells with critical roles in enforcing
immunity, barrier integrity and tissue homeostasis along the gastrointestinal tract. ILC3 are …

Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut

A Das, GU Martinez-Ruiz, N Bouladoux, A Stacy… - Immunity, 2024 - cell.com
Group 3 innate lymphoid cells (ILC3) are the major subset of gut-resident ILC with essential
roles in infections and tissue repair, but how they adapt to the gut environment to maintain …

Inhibition of Piezo1 ameliorates intestinal inflammation and limits the activation of group 3 innate lymphoid cells in experimental colitis

C Liu, Y **a, S Fu, F Meng, B Feng, L Xu, L Li… - Journal of Innate …, 2023 - karger.com
Piezo1, the mechanosensory ion channel, has attracted increasing attention for its essential
roles in various inflammatory responses and immune-related diseases. Although most of the …