Metabolic control of innate lymphoid cells in health and disease
Innate lymphoid cells (ILCs) are a family of predominantly tissue-resident lymphocytes that
critically orchestrate immunity, inflammation, tolerance and repair at barrier surfaces of the …
critically orchestrate immunity, inflammation, tolerance and repair at barrier surfaces of the …
[HTML][HTML] Innate lymphoid cell plasticity in mucosal infections
AA Korchagina, E Koroleva, AV Tumanov - Microorganisms, 2023 - mdpi.com
Mucosal tissue homeostasis is a dynamic process that involves multiple mechanisms
including regulation of innate lymphoid cells (ILCs). ILCs are mostly tissue-resident cells …
including regulation of innate lymphoid cells (ILCs). ILCs are mostly tissue-resident cells …
[HTML][HTML] Dietary butyrate, lauric acid and stearic acid improve gut morphology and epithelial cell turnover in weaned piglets
This study was to evaluate the effects of the supplementation of saturated fatty acids with
different chain lengths on growth performance, intestinal morphology, epithelial cell …
different chain lengths on growth performance, intestinal morphology, epithelial cell …
mTORC2 acts as a gatekeeper for mTORC1 deficiency-mediated impairments in ILC3 development
Y Deng, S Wu, H Peng, L Tian, Y Li, Y Yang… - Acta Pharmacologica …, 2023 - nature.com
Group 3 innate lymphoid cells (ILC3s) are mediators of intestinal immunity and barrier
function. Recent studies have investigated the role of the mammalian target of rapamycin …
function. Recent studies have investigated the role of the mammalian target of rapamycin …
Hyperbaric oxygen augments susceptibility to C. difficile infection by impairing gut microbiota ability to stimulate the HIF-1α-IL-22 axis in ILC3
Hyperbaric oxygen (HBO) therapy is a well-established method for improving tissue
oxygenation and is typically used for the treatment of various inflammatory conditions …
oxygenation and is typically used for the treatment of various inflammatory conditions …
Role of innate lymphoid cells in obesity and insulin resistance
H Chen, L Sun, L Feng, Y Yin, W Zhang - Frontiers in Endocrinology, 2022 - frontiersin.org
Obesity, a growing chronic metabolic disease, greatly increases the risk of metabolic
syndrome which includes type 2 diabetes, fatty liver and cardiovascular diseases. Obesity …
syndrome which includes type 2 diabetes, fatty liver and cardiovascular diseases. Obesity …
[HTML][HTML] IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis
A Valle-Noguera, L Sancho-Temiño… - Cell Reports, 2023 - cell.com
Group 3 innate lymphoid cells (ILC3s) are vital for defending tissue barriers from invading
pathogens. Hypoxia influences the production of intestinal ILC3-derived cytokines by …
pathogens. Hypoxia influences the production of intestinal ILC3-derived cytokines by …
[HTML][HTML] Bcl-2 supports survival and metabolic fitness of quiescent tissue-resident ILC3
JI King, F Melo-Gonzalez, B Malengier-Devlies… - Mucosal …, 2023 - Elsevier
Group 3 innate lymphoid cells (ILC3) are potent effector cells with critical roles in enforcing
immunity, barrier integrity and tissue homeostasis along the gastrointestinal tract. ILC3 are …
immunity, barrier integrity and tissue homeostasis along the gastrointestinal tract. ILC3 are …
Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut
Group 3 innate lymphoid cells (ILC3) are the major subset of gut-resident ILC with essential
roles in infections and tissue repair, but how they adapt to the gut environment to maintain …
roles in infections and tissue repair, but how they adapt to the gut environment to maintain …
Inhibition of Piezo1 ameliorates intestinal inflammation and limits the activation of group 3 innate lymphoid cells in experimental colitis
C Liu, Y **a, S Fu, F Meng, B Feng, L Xu, L Li… - Journal of Innate …, 2023 - karger.com
Piezo1, the mechanosensory ion channel, has attracted increasing attention for its essential
roles in various inflammatory responses and immune-related diseases. Although most of the …
roles in various inflammatory responses and immune-related diseases. Although most of the …