Obesity is a pandemic of the 21st century, and the prevalence of this metabolic condition has
enormously increased over the past few decades. Obesity is associated with a number of …

Cellular turnover is fundamental for tissue homeostasis and integrity. Adipocyte turnover,
accounting for 4% of the total cellular mass turnover in humans, is essential for adipose …

Programmed cell death (PCD) plays a crucial role in maintaining tissue homeostasis, with its
primary forms including apoptosis, pyroptosis, and necroptosis. The caspase family is …

Over 20 million adults and 6 million children in the United States (US) have asthma, a
chronic respiratory disease characterized by airway inflammation, bronchoconstriction, and …

Purpose Injectable deoxycholic acid (DA) has been approved for removing excess
submental fat and is off-label for local adipose tissue reduction. Conventional DA injections …

Hepatocellular carcinoma (HCC) represents the most prevalent form of primary liver cancer
and has a high mortality rate. Caspase-8 plays a pivotal role in an array of cellular signaling …

Programmed cell death (PCD) has emerged as a critical regulatory mechanism in the
initiation and progression of various pathological conditions. PCD in microglia, including …

Objective To investigate whether tricyclic decylbenzoxazole (TDB) regulates liver cancer cell
proliferation and apoptosis through p300-mediated FOXO acetylation. Methods Sequencing …

Ethnopharmacological relevance Psoriasis is characterized by hyperkeratosis that produces
the classic silvery scales, and the pathogenesis of psoriasis involves abnormal proliferation …

Background Noncommunicable disease, in particular cardiovascular disease (CVD) and
diabetes are a major cause of morbidity and mortality in the world. Short and long sleep …