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Respiratory syncytial virus (RSV): a scourge from infancy to old age
JA Coultas, R Smyth, PJ Openshaw - Thorax, 2019 - thorax.bmj.com
Respiratory syncytial virus (RSV) is the most common single cause of respiratory
hospitalisation of infants and is the second largest cause of lower respiratory infection …
hospitalisation of infants and is the second largest cause of lower respiratory infection …
[HTML][HTML] SARS-CoV-2 spike promotes inflammation and apoptosis through autophagy by ROS-suppressed PI3K/AKT/mTOR signaling
F Li, J Li, PH Wang, N Yang, J Huang, J Ou, T Xu… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Background Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection-
induced inflammatory responses are largely responsible for the death of novel coronavirus …
induced inflammatory responses are largely responsible for the death of novel coronavirus …
Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response
Severe respiratory syncytial virus (RSV) infection is a major cause of morbidity and mortality
in infants< 2 years-old. Here we describe that high-fiber diet protects mice from RSV …
in infants< 2 years-old. Here we describe that high-fiber diet protects mice from RSV …
Disease severity in respiratory syncytial virus infection: role of host genetic variation
Respiratory syncytial virus (RSV) infection is the most common cause of bronchiolitis and
pneumonia in the pediatric population worldwide. The immunopathology of RSV infection …
pneumonia in the pediatric population worldwide. The immunopathology of RSV infection …
Discrete viral E2 lysine residues and scavenger receptor MARCO are required for clearance of circulating alphaviruses
KS Carpentier, BJ Davenport, KC Haist, MK McCarthy… - Elife, 2019 - elifesciences.org
The magnitude and duration of vertebrate viremia is a critical determinant of arbovirus
transmission, geographic spread, and disease severity. We find that multiple alphaviruses …
transmission, geographic spread, and disease severity. We find that multiple alphaviruses …
Small animal models of respiratory viral infection related to asthma
M Han, C Rajput, T Ishikawa, CR Jarman, J Lee… - Viruses, 2018 - mdpi.com
Respiratory viral infections are strongly associated with asthma exacerbations. Rhinovirus is
most frequently-detected pathogen; followed by respiratory syncytial virus; …
most frequently-detected pathogen; followed by respiratory syncytial virus; …
MARCO+ lymphatic endothelial cells sequester arthritogenic alphaviruses to limit viremia and viral dissemination
KS Carpentier, RM Sheridan, CJ Lucas… - The EMBO …, 2021 - embopress.org
Viremia in the vertebrate host is a major determinant of arboviral reservoir competency,
transmission efficiency, and disease severity. However, immune mechanisms that control …
transmission efficiency, and disease severity. However, immune mechanisms that control …
p53-responsive TLR8 SNP enhances human innate immune response to respiratory syncytial virus
D Menendez, J Snipe, J Marzec, CL Innes… - The Journal of Clinical …, 2019 - jci.org
The Toll-like receptor 8 (TLR8) has an important role in innate immune responses to RNA
viral infections, including respiratory syncytial virus (RSV). We previously reported that TLR8 …
viral infections, including respiratory syncytial virus (RSV). We previously reported that TLR8 …
The Notch ligand DNER regulates macrophage IFNγ release in chronic obstructive pulmonary disease
Abstract Background Chronic Obstructive Pulmonary Disease (COPD) is the third leading
cause of death worldwide with no curative therapy. A non-canonical Notch ligand, DNER …
cause of death worldwide with no curative therapy. A non-canonical Notch ligand, DNER …
Inter-individual variation in health and disease associated with pulmonary infectious agents
KC Verhein, HL Vellers, SR Kleeberger - Mammalian Genome, 2018 - Springer
Respiratory infectious diseases resulting from bacterial or viral pathogens such as
Mycobacterium tuberculosis, Streptococcus pneumoniae, respiratory syncytial virus (RSV) …
Mycobacterium tuberculosis, Streptococcus pneumoniae, respiratory syncytial virus (RSV) …