Acute myeloid leukemia (AML) is a hematopoietic disorder characterized by numerous
cytogenetic and molecular aberrations that accounts for~ 25% of childhood leukemia …

Recent advances in the field of cancer genome analysis revolutionized the picture we have
of acute myeloid leukemia (AML). Pan-genomic studies, using either single nucleotide …

ABSTRACT RUNX1:: RUNX1T1 (R:: RT1) acute myeloid leukaemia (AML) remains a clinical
challenge, and further research is required to model and understand leukaemogenesis …

Acute myeloid leukemia (AML), the most common acute leukemia in adults, is a
heterogeneous malignant clonal disorder arising from multipotent hematopoietic progenitor …

The prognostic significance of loss of X chromosome (-X) in t (8; 21) acute myeloid leukemia
(AML) remains unclear. We evaluated the role of-X in 158 female patients with t (8; 21) AML …

The prognostic significance of loss of the Y chromosome (LOY) in patients with t (8; 21)(q22;
q22) acute myeloid leukemia (AML) remains poorly understood. To investigate this issue …

Introduction Gene rearrangements of acute myeloid leukemia (AML) play a significant role in
categorizing patients and provide valuable information about prognosis and treatment …

Research on the comprehensive integration of clinical and genomic characteristics in
patients with core binding factor acute myeloid leukemia (CBF-AML) is limited. Clinical and …

Background: Acute myeloid leukemia with the t (8; 21)(q22; q22) rearrangement (RUNX1-
RUNX1T1 (+) AML) is known to have a favorable prognosis. Our study aimed to determine …

Dear Editors: The core-binding factor (CBF) and acute myeloid leukemias (AML) are
considered a distinct subgroup of AML due to similar molecular pathogenesis and clinical …