Carbohydrate-active enzymes (CAZymes) in the gut microbiome
The 1013–1014 microorganisms present in the human gut (collectively known as the human
gut microbiota) dedicate substantial percentages of their genomes to the degradation and …
gut microbiota) dedicate substantial percentages of their genomes to the degradation and …
[HTML][HTML] Biocatalysis
Biocatalysis has become an important aspect of modern organic synthesis, both in
academia and across the chemical and pharmaceutical industries. Its success has been …
academia and across the chemical and pharmaceutical industries. Its success has been …
[HTML][HTML] ABO genotype alters the gut microbiota by regulating GalNAc levels in pigs
H Yang, J Wu, X Huang, Y Zhou, Y Zhang, M Liu, Q Liu… - Nature, 2022 - nature.com
The composition of the intestinal microbiome varies considerably between individuals and is
correlated with health. Understanding the extent to which, and how, host genetics …
correlated with health. Understanding the extent to which, and how, host genetics …
[HTML][HTML] Host genetic regulation of human gut microbial structural variation
Although the impact of host genetics on gut microbial diversity and the abundance of specific
taxa is well established,,,,–, little is known about how host genetics regulates the genetic …
taxa is well established,,,,–, little is known about how host genetics regulates the genetic …
Carbohydrate-active enzymes from Akkermansia muciniphila break down mucin O-glycans to completion
Akkermansia muciniphila is a human microbial symbiont residing in the mucosal layer of the
large intestine. Its main carbon source is the highly heterogeneous mucin glycoprotein, and …
large intestine. Its main carbon source is the highly heterogeneous mucin glycoprotein, and …
Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs
A Wang, RVP Ribeiro, A Ali, E Brambate… - Science Translational …, 2022 - science.org
Donor organ allocation is dependent on ABO matching, restricting the opportunity for some
patients to receive a life-saving transplant. The enzymes FpGalNAc deacetylase and …
patients to receive a life-saving transplant. The enzymes FpGalNAc deacetylase and …
Turning universal O into rare Bombay type blood
Red blood cell antigens play critical roles in blood transfusion since donor incompatibilities
can be lethal. Recipients with the rare total deficiency in H antigen, the Oh Bombay …
can be lethal. Recipients with the rare total deficiency in H antigen, the Oh Bombay …
Mucin utilization by gut microbiota: recent advances on characterization of key enzymes
G Raba, AS Luis - Essays in Biochemistry, 2023 - portlandpress.com
The gut microbiota interacts with the host through the mucus that covers and protects the
gastrointestinal epithelium. The main component of the mucus are mucins, glycoproteins …
gastrointestinal epithelium. The main component of the mucus are mucins, glycoproteins …
Improving normothermic machine perfusion and blood transfusion through biocompatible blood silicification
The growing world population and increasing life expectancy are driving the need to
improve the quality of blood transfusion, organ transplantation, and preservation. Here, to …
improve the quality of blood transfusion, organ transplantation, and preservation. Here, to …
Enzymatic Adaptation of Bifidobacterium bifidum to Host Glycans, Viewed from Glycoside Hydrolyases and Carbohydrate-Binding Modules
Certain species of the genus Bifidobacterium represent human symbionts. Many studies
have shown that the establishment of symbiosis with such bifidobacterial species confers …
have shown that the establishment of symbiosis with such bifidobacterial species confers …