Background Because of the disability associated with surgery for anal fissure and the risk of
incontinence, medical alternatives for surgery have been sought. Most recently …

Background Anal fissure has a very large number of treatment options. The choice is difficult.
In an effort to assist in that, choice presented here is a systematic review and meta-analysis …

Directed searches of the embedded references from the primary articles were also
performed in certain circumstances. Prospective, randomized, controlled trials and meta …

MATERIALS AND METHODS These guidelines were built upon the previous ASCRS
“Clinical Practice Guideline for the Management of Anal Fissures,” published in 2017. 6 In …

Supplying lavish color illustrations that fully detail key anatomical structures and pathology,
this Third Edition encompasses the complete range of diseases encountered by colorectal …

The American Society of Colon and Rectal Surgeons is dedicated to ensuring high-quality
patient care by advancing the science, prevention, and management of disorders and …

INTRODUCTION: Chemical sphincterotomy has proved effective in treating chronic anal
fissure. Glyceryl trinitrate is the most widely used agent, and topical 0.2 percent glyceryl …

Anal fissure is one of the most common and painful proctologic diseases. Its treatment has
long been discussed and several different therapeutic options have been proposed. In the …

Background The treatment of chronic anal fissure has shifted in recent years from surgical to
medical. Methods A Medline search of studies relevant to modern management of chronic …

Purpose: This is a meta-analysis of randomized, controlled trials to assess the efficacy and
morbidity of medical therapies for anal fissure. Methods: Medline and the Cochrane …