HIV-1 drug resistance and resistance testing
DS Clutter, MR Jordan, S Bertagnolio… - Infection, Genetics and …, 2016 - Elsevier
The global scale-up of antiretroviral (ARV) therapy (ART) has led to dramatic reductions in
HIV-1 mortality and incidence. However, HIV drug resistance (HIVDR) poses a potential …
HIV-1 mortality and incidence. However, HIV drug resistance (HIVDR) poses a potential …
COMET: adaptive context-based modeling for ultrafast HIV-1 subtype identification
D Struck, G Lawyer, AM Ternes, JC Schmit… - Nucleic acids …, 2014 - academic.oup.com
Viral sequence classification has wide applications in clinical, epidemiological, structural
and functional categorization studies. Most existing approaches rely on an initial alignment …
and functional categorization studies. Most existing approaches rely on an initial alignment …
[HTML][HTML] HIV drug resistance following a decade of the free antiretroviral therapy programme in India: a review
Objective The objective of this review was to assess the burden of HIV drug resistance
mutations (DRM) in Indian adults exposed to first-line antiretroviral therapy (ART) as per …
mutations (DRM) in Indian adults exposed to first-line antiretroviral therapy (ART) as per …
VIRULIGN: fast codon-correct alignment and annotation of viral genomes
Virus sequence data are an essential resource for reconstructing spatiotemporal dynamics
of viral spread as well as to inform treatment and prevention strategies. However, the …
of viral spread as well as to inform treatment and prevention strategies. However, the …
HIV-1 antiretroviral drug resistance patterns in patients failing NNRTI-based treatment: results from a national survey in South Africa
K Steegen, M Bronze… - Journal of …, 2016 - academic.oup.com
Background Routine HIV-1 antiretroviral drug resistance testing for patients failing NNRTI-
based regimens is not recommended in resource-limited settings. Therefore, surveys are …
based regimens is not recommended in resource-limited settings. Therefore, surveys are …
HIV transmission dynamics and population-wide drug resistance in rural South Africa
SA Kemp, K Kamelian, DF Cuadros… - Nature …, 2024 - nature.com
Despite expanded antiretroviral therapy (ART) in South Africa, HIV-1 transmission persists.
Integrase strand transfer inhibitors (INSTI) and long-acting injectables offer potential for …
Integrase strand transfer inhibitors (INSTI) and long-acting injectables offer potential for …
High-levels of acquired drug resistance in adult patients failing first-line antiretroviral therapy in a rural HIV treatment programme in KwaZulu-Natal, South Africa
Objective To determine the frequency and patterns of acquired antiretroviral drug resistance
in a rural primary health care programme in South Africa. Design Cross-sectional study …
in a rural primary health care programme in South Africa. Design Cross-sectional study …
High prevalence of the K65R mutation in HIV-1 subtype C infected patients failing tenofovir-based first-line regimens in South Africa
L Skhosana, K Steegen, M Bronze, A Lukhwareni… - PloS one, 2015 - journals.plos.org
Background Tenofovir (TDF) has replaced stavudine (d4T) as the preferred nucleoside
reverse transcriptase inhibitor (NRTI) in first-line regimens in South Africa, but limited …
reverse transcriptase inhibitor (NRTI) in first-line regimens in South Africa, but limited …
Cohort profile: a European multidisciplinary network for the fight against HIV drug resistance (Euresist network)
The EuResist cohort was established in 2006 with the purpose of develo** a clinical
decision-support tool predicting the most effective antiretroviral therapy (ART) for persons …
decision-support tool predicting the most effective antiretroviral therapy (ART) for persons …
Treatment failure and drug resistance in HIV‐positive patients on tenofovir‐based first‐line antiretroviral therapy in western Kenya
K Brooks, L Diero, A DeLong… - Journal of the …, 2016 - Wiley Online Library
Introduction Tenofovir‐based first‐line antiretroviral therapy (ART) is recommended globally.
To evaluate the impact of its incorporation into the World Health Organization (WHO) …
To evaluate the impact of its incorporation into the World Health Organization (WHO) …