Nanopore-based technologies beyond DNA sequencing
Inspired by the biological processes of molecular recognition and transportation across
membranes, nanopore techniques have evolved in recent decades as ultrasensitive …
membranes, nanopore techniques have evolved in recent decades as ultrasensitive …
Nonspecific binding—fundamental concepts and consequences for biosensing applications
A Frutiger, A Tanno, S Hwu, RF Tiefenauer… - Chemical …, 2021 - ACS Publications
Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …
through precise control of biomolecules in space and time. Artificial systems such as …
Beyond mass spectrometry, the next step in proteomics
Proteins can be the root cause of a disease, and they can be used to cure it. The need to
identify these critical actors was recognized early (1951) by Sanger; the first biopolymer …
identify these critical actors was recognized early (1951) by Sanger; the first biopolymer …
Protein identification by nanopore peptide profiling
Nanopores are single-molecule sensors used in nucleic acid analysis, whereas their
applicability towards full protein identification has yet to be demonstrated. Here, we show …
applicability towards full protein identification has yet to be demonstrated. Here, we show …
Bioinspired super‐wettability from fundamental research to practical applications
Engineered wettability is a traditional, yet key issue in surface science and attracts
tremendous interest in solving large‐scale practical problems. Recently, different super …
tremendous interest in solving large‐scale practical problems. Recently, different super …
Highly shape-and size-tunable membrane nanopores made with DNA
Membrane nanopores are key for molecular transport in biology, portable DNA sequencing,,–
, label-free single-molecule analysis,,,,,,,,–and nanomedicine. Transport traditionally relies …
, label-free single-molecule analysis,,,,,,,,–and nanomedicine. Transport traditionally relies …
Nanopore-based fourth-generation DNA sequencing technology
Nanopore-based sequencers, as the fourth-generation DNA sequencing technology, have
the potential to quickly and reliably sequence the entire human genome for less than 1000 …
the potential to quickly and reliably sequence the entire human genome for less than 1000 …
Building membrane nanopores
S Howorka - Nature nanotechnology, 2017 - nature.com
Membrane nanopores—hollow nanoscale barrels that puncture biological or synthetic
membranes—have become powerful tools in chemical-and biosensing, and have achieved …
membranes—have become powerful tools in chemical-and biosensing, and have achieved …
Identification of single amino acid differences in uniformly charged homopolymeric peptides with aerolysin nanopore
There are still unmet needs in finding new technologies for biomedical diagnostic and
industrial applications. A technology allowing the analysis of size and sequence of short …
industrial applications. A technology allowing the analysis of size and sequence of short …
The application of single molecule nanopore sensing for quantitative analysis
Nanopore-based sensors typically work by monitoring transient pulses in conductance via
current–time traces as molecules translocate through the nanopore. The unique property of …
current–time traces as molecules translocate through the nanopore. The unique property of …