Complex genetic and physiological variations as well as environmental factors that drive
emergence of chromosomal instability, development of unscheduled cell death, skewed …

To date, 18 distinct receptor tyrosine kinases (RTKs) are reported to be trafficked from the
cell surface to the nucleus in response to ligand binding or heterologous agonist exposure …

The receptor tyrosine kinase ERBB4, a member of the epidermal growth factor receptor
(EGFR) family, is unusual in that ERBB4 can undergo intramembrane proteolysis, releasing …

Usage of presumed 5′ UTR or downstream in-frame AUG codons, next to non-AUG codons
as translation start codons contributes to the diversity of a proteome as protein isoforms …

Intracellular localization has been reported for over three‐quarters of receptor tyrosine
kinase (RTK) families in response to environmental stimuli. Internalized RTK may bind to …

Axons and Schwann cells exist in a highly interdependent relationship: damage to one cell
type invariably leads to pathophysiological changes in the other. Greater understanding of …

Migration of human glioma cells (hGCs) within the brain parenchyma makes glioblastoma
one of the most aggressive and lethal tumors. Studies of the cellular and molecular …

It is well established that the epidermal growth factor (EGF) receptor, receptor tyrosine-
protein kinase erbB-2 (ERBB2)/human EGF receptor 2 (HER2), and, to a lesser extent …

Following spinal cord injury (SCI), a multitude of intrinsic and extrinsic factors adversely
affect the gene programs that govern the expression of regeneration-associated genes …

The role of HER4 in breast cancer is controversial and its role in relation to trastuzumab
resistance remains unclear. We showed that trastuzumab treatment and its acquired …