Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …

We present ilastik, an easy-to-use interactive tool that brings machine-learning-based (bio)
image analysis to end users without substantial computational expertise. It contains pre …

We present LABKIT, a user-friendly Fiji plugin for the segmentation of microscopy image
data. It offers easy to use manual and automated image segmentation routines that can be …

Induced pluripotent stem cell (iPSC)-derived organoids provide models to study human
organ development. Single-cell transcriptomics enable highly resolved descriptions of cell …

State-of-the-art tissue-clearing methods provide subcellular-level optical access to intact
tissues from individual organs and even to some entire mammals. When combined with light …

The mouse embryo has long been central to the study of mammalian development;
however, elucidating the cell behaviors governing gastrulation and the formation of tissues …

Tissue engineering research has undergone to a revolutionary improvement, thanks to
technological advancements, such as the introduction of bioprinting technologies. The ability …

Light-sheet imaging of cleared and expanded samples creates terabyte-sized datasets that
consist of many unaligned three-dimensional image tiles, which must be reconstructed …

The human brain has undergone rapid expansion since humans diverged from other great
apes, but the mechanism of this human-specific enlargement is still unknown. Here, we use …

Virtual reality (VR) has recently become an affordable technology. A wide range of options
are available to access this unique visualization medium, from simple cardboard inserts for …