p-Cresyl Sulfate
If chronic kidney disease (CKD) is associated with an impairment of kidney function, several
uremic solutes are retained. Some of these exert toxic effects, which are called uremic …
uremic solutes are retained. Some of these exert toxic effects, which are called uremic …
Future avenues to decrease uremic toxin concentration
RC Vanholder, S Eloot, GLRL Glorieux - American Journal of Kidney …, 2016 - Elsevier
In this article, we review approaches for decreasing uremic solute concentrations in chronic
kidney disease and in particular, in end-stage renal disease (ESRD). The rationale to do so …
kidney disease and in particular, in end-stage renal disease (ESRD). The rationale to do so …
Challenges of reducing protein-bound uremic toxin levels in chronic kidney disease and end stage renal disease
The prevalence of chronic kidney disease (CKD) in the worldwide population is currently
estimated between 11% and 13%. Adequate renal clearance is compromised in these …
estimated between 11% and 13%. Adequate renal clearance is compromised in these …
Using binding competitors of albumin to promote the removal of protein-bound uremic toxins in hemodialysis: hope or pipe dream?
Chronic kidney disease is associated with the accumulation of a large range of uremic
retention solutes as referred to as uremic toxins. Some of these compounds belong to the …
retention solutes as referred to as uremic toxins. Some of these compounds belong to the …
Removal of uremic solutes from dialysate by activated carbon
S Lee, TL Sirich, IJ Blanco, NS Plummer… - Clinical Journal of the …, 2022 - journals.lww.com
Results Activated carbon initially adsorbed the majority, but not all, of 264 uremic solutes
examined. Solute adsorption fell, however, as increasing volumes of dialysate were …
examined. Solute adsorption fell, however, as increasing volumes of dialysate were …
Nanobody-Based high-performance immunosorbent for selective beta 2-microglobulin purification from blood
C Huang, J Ren, F Ji, S Muyldermans, L Jia - Acta Biomaterialia, 2020 - Elsevier
Abstract Removing β2-microglobulin (β2M) from blood circulation is considered to be the
most effective method to delay the occurrence of dialysis-related amyloidosis (DRA). The …
most effective method to delay the occurrence of dialysis-related amyloidosis (DRA). The …
Review of protein-bound toxins, possibility for blood purification therapy
N Neirynck, G Glorieux, E Schepers, A Pletinck… - Blood purification, 2013 - karger.com
Protein-bound uremic retention solutes, ie phenolic compounds, such as p-cresylsulfate,
and indolic compounds, such as indoxyl sulfate, have been intensively studied in recent …
and indolic compounds, such as indoxyl sulfate, have been intensively studied in recent …
Increasing haemodialytic clearances as residual renal function declines: An incremental approach
K Tangvoraphonkchai, A Davenport - Blood Purification, 2017 - karger.com
Many patients with chronic kidney disease start undergoing thrice-weekly haemodialysis
(HD), aiming for an HD sessional dialyzer urea clearance target, irrespective of whether they …
(HD), aiming for an HD sessional dialyzer urea clearance target, irrespective of whether they …
Uremia-related oxidative stress in leukocytes is not triggered by β2-microglobulin
N Neirynck, G Glorieux, J Boelaert, E Schepers… - Journal of Renal …, 2013 - Elsevier
Background Chronic kidney disease (CKD) is characterized by low-grade inflammation and
increased risk for cardiovascular disease. The interest in β2-microglobulin (B2M) as a …
increased risk for cardiovascular disease. The interest in β2-microglobulin (B2M) as a …
Inflammatory response to sorbent hemodialysis
L Rosales, S Thijssen, A Kruse, MH Sipahioglu… - Asaio …, 2015 - journals.lww.com
Inflammation is common and associated with morbidity and mortality in hemodialysis (HD)
patients. Exposure to endotoxin contained in the dialysate may trigger inflammation …
patients. Exposure to endotoxin contained in the dialysate may trigger inflammation …