Alzheimer's disease is incurable but preventable

JC De la Torre - Journal of Alzheimer's disease, 2010 - content.iospress.com
The dramatic rising incidence and costs of Alzheimer's disease (AD) require that research
efforts and funding be primarily directed on either finding a cure or applying preventive …

Imaging retinal microvascular manifestations of carotid artery disease in older adults: from diagnosis of ocular complications to understanding microvascular …

L István, C Czakó, Á Élő, Z Mihály, P Sótonyi, A Varga… - Geroscience, 2021 - Springer
Carotid artery stenosis (CAS) is a consequence of systemic atherosclerotic disease affecting
the aging populations of the Western world. CAS is frequently associated with cognitive …

Neurocognitive functioning and cerebrovascular reactivity after carotid endarterectomy

S Lattanzi, L Carbonari, G Pagliariccio, M Bartolini… - Neurology, 2018 - neurology.org
Objective To evaluate in patients with TIA and ipsilateral high-grade internal carotid artery
(ICA) stenosis whether changes in cognitive performance and cerebral hemodynamics …

Severe carotid stenosis and impaired cerebral hemodynamics can influence cognitive deterioration

S Balestrini, C Perozzi, C Altamura, F Vernieri, S Luzzi… - Neurology, 2013 - neurology.org
Objective: To evaluate whether severe carotid stenosis and related hemodynamics
impairment may increase the risk of cognitive deterioration in asymptomatic subjects …

Impairments in cognitive function and brain connectivity in severe asymptomatic carotid stenosis

HL Cheng, CJ Lin, BW Soong, PN Wang, FC Chang… - Stroke, 2012 - ahajournals.org
Background and Purpose—Severe asymptomatic carotid stenosis has been associated with
cognitive impairment, but it is unknown whether this association is attributable to effects on …

The role of carotid atherosclerosis in Alzheimer's disease progression

M Silvestrini, G Viticchi, L Falsetti… - Journal of …, 2011 - journals.sagepub.com
The aim of this 12-month prospective study was to establish whether severe internal carotid
artery stenosis is associated with faster progression of the cognitive impairment in patients …

Association between asymptomatic carotid stenosis and cognitive function: a systematic review

XL Chang, HQ Zhou, CY Lei, B Wu, YC Chen… - Neuroscience & …, 2013 - Elsevier
Background Asymptomatic carotid stenosis (CS), traditionally considered clinically silent,
may be an independent risk factor for a cognitive impairment. Methods To determine …

Impact of carotid stenosis on cerebral hemodynamic failure and cognitive impairment progression: a narrative review

G Viticchi, L Falsetti, E Potente… - Annals of …, 2021 - pmc.ncbi.nlm.nih.gov
Carotid atherosclerosis has a relevant impact on cerebral blood flow regulation. There is
accruing evidence that hemodynamic impairment related to the presence of a significant …

Impairments in brain perfusion, metabolites, functional connectivity, and cognition in severe asymptomatic carotid stenosis patients: an integrated MRI study

T Wang, F **ao, G Wu, J Fang, Z Sun, H Feng… - Neural …, 2017 - Wiley Online Library
Carotid artery stenosis without transient ischemic attack (TIA) or stroke is considered as
“asymptomatic.” However, recent studies have demonstrated that these asymptomatic …

Connectivity features for identifying cognitive impairment in presymptomatic carotid stenosis

CJ Lin, PC Tu, CM Chern, FJ Hsiao, FC Chang… - PLoS …, 2014 - journals.plos.org
Severe asymptomatic stenosis of the internal carotid artery (ICA) leads to increased
incidence of mild cognitive impairment (MCI) likely through silent embolic infarcts and/or …