Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration?

FG Teixeira, MM Carvalho, N Sousa… - Cellular and Molecular …, 2013 - Springer
The low regeneration potential of the central nervous system (CNS) represents a challenge
for the development of new therapeutic strategies. Mesenchymal stem cells (MSCs) have …

[HTML][HTML] Stem cell treatment of degenerative eye disease

B Mead, M Berry, A Logan, RAH Scott, W Leadbeater… - Stem cell …, 2015 - Elsevier
Stem cell therapies are being explored extensively as treatments for degenerative eye
disease, either for replacing lost neurons, restoring neural circuits or, based on more recent …

Paracrine-mediated neuroprotection and neuritogenesis of axotomised retinal ganglion cells by human dental pulp stem cells: comparison with human bone marrow …

B Mead, A Logan, M Berry, W Leadbeater… - PloS one, 2014 - journals.plos.org
We have investigated and compared the neurotrophic activity of human dental pulp stem
cells (hDPSC), human bone marrow-derived mesenchymal stem cells (hBMSC) and human …

Current strategies to enhance adipose stem cell function: an update

Y Seo, TH Shin, HS Kim - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) emerged as a promising therapeutic tool targeting a variety
of inflammatory disorders due to their multiple remarkable properties, such as superior …

[HTML][HTML] Mesenchymal stem cells in the treatment of spinal cord injuries: A review

VR Dasari, KK Veeravalli, DH Dinh - World journal of stem cells, 2014 - ncbi.nlm.nih.gov
With technological advances in basic research, the intricate mechanism of secondary
delayed spinal cord injury (SCI) continues to unravel at a rapid pace. However, despite our …

Hydrogels and cell based therapies in spinal cord injury regeneration

RC Assunção-Silva, ED Gomes, N Sousa… - Stem cells …, 2015 - Wiley Online Library
Spinal cord injury (SCI) is a central nervous system‐(CNS‐) related disorder for which there
is yet no successful treatment. Within the past several years, cell‐based therapies have …

Advances in stem cell therapy for spinal cord injury

AJ Mothe, CH Tator - The Journal of clinical investigation, 2012 - Am Soc Clin Investig
Spinal cord injury (SCI) is a devastating condition producing great personal and societal
costs and for which there is no effective treatment. Stem cell transplantation is a promising …

Adipose‐derived stem cells in tissue regeneration: a review

P Zuk - International Scholarly Research Notices, 2013 - Wiley Online Library
In 2001, researchers at the University of California, Los Angeles, described the isolation of a
new population of adult stem cells from liposuctioned adipose tissue. These stem cells, now …

Transplantation of mesenchymal stromal cells in patients with amyotrophic lateral sclerosis: results of phase I/IIa clinical trial

E Syková, P Rychmach, I Drahorádová… - Cell …, 2017 - journals.sagepub.com
Amyotrophic lateral sclerosis (ALS) is a progressive untreatable neurodegenerative
disorder, leading to the death of the cortical and spinal motoneurons (MNs). Bone marrow …

Differentiation of human mesenchymal stem cells towards neuronal lineage: clinical trials in nervous system disorders

R Hernández, C Jiménez-Luna… - Biomolecules & …, 2019 - pmc.ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have been proposed as an alternative therapy to be
applied into several pathologies of the nervous system. These cells can be obtained from …