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PAK4 in cancer development: Emerging player and therapeutic opportunities
Y Yuan, H Zhang, D Li, Y Li, F Lin, Y Wang, H Song… - Cancer letters, 2022 - Elsevier
Abstract p21-activated kinase 4 (PAK4), a member of the serine-threonine kinase family,
was initially identified as a protein kinase that functions downstream of the Rho GTPases …
was initially identified as a protein kinase that functions downstream of the Rho GTPases …
miRNA signature in glioblastoma: Potential biomarkers and therapeutic targets
MicroRNAs (miRNAs) are transcripts with sizes of about 22 nucleotides, which are produced
through a multistep process in the nucleus and cytoplasm. These transcripts modulate the …
through a multistep process in the nucleus and cytoplasm. These transcripts modulate the …
Long non-coding RNA MEG3 promotes cerebral ischemia-reperfusion injury through increasing pyroptosis by targeting miR-485/AIM2 axis
J Liang, Q Wang, JQ Li, T Guo, D Yu - Experimental Neurology, 2020 - Elsevier
Objective Inflammasome contributes to ischemic brain injury by inducing pyroptosis and
inflammation. The aim of this study is to unravel the mechanism of long non-coding RNA …
inflammation. The aim of this study is to unravel the mechanism of long non-coding RNA …
[HTML][HTML] NLRP3 in human glioma is correlated with increased WHO grade, and regulates cellular proliferation, apoptosis and metastasis via epithelial-mesenchymal …
XF Yin, Q Zhang, ZY Chen… - International …, 2018 - spandidos-publications.com
Glioma is the most prevalent and fatal primary tumor of the central nervous system in adults,
while the development of effective therapeutic strategies in clinical practice remain a …
while the development of effective therapeutic strategies in clinical practice remain a …
PAK4, a target of miR-9-5p, promotes cell proliferation and inhibits apoptosis in colorectal cancer
M Wang, Q Gao, Y Chen, Z Li, L Yue, Y Cao - Cellular & molecular biology …, 2019 - Springer
Background Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide.
P21-activated kinase 4 (PAK4) and miR-9-5p have emerged as attractive therapeutic targets …
P21-activated kinase 4 (PAK4) and miR-9-5p have emerged as attractive therapeutic targets …
Linc01234 promotes cell proliferation and metastasis in oral squamous cell carcinoma via miR-433/PAK4 axis
D Liu, X Jian, P Xu, R Zhu, Y Wang - BMC cancer, 2020 - Springer
Background Increasing studies have demonstrated that long non-coding RNAs (lncRNAs)
play an important role in tumor progression. However, the potential biological functions and …
play an important role in tumor progression. However, the potential biological functions and …
[PDF][PDF] RETRACTED ARTICLE: LINC01224 Exhibits Cancer-Promoting Activity in Epithelial Ovarian Cancer Through microRNA-485-5p-Mediated PAK4 Upregulation
S **ng, Y Zhang, J Zhang - OncoTargets and therapy, 2020 - Taylor & Francis
**ng S, Zhang Y, Zhang J. Onco Targets Ther. 2020; 13: 5643–5655. The Editor and
Publisher of OncoTargets and Therapy wish to retract the published article. Concerns were …
Publisher of OncoTargets and Therapy wish to retract the published article. Concerns were …
Long non-coding RNA CRNDE promotes colorectal carcinoma cell progression and paclitaxel resistance by regulating miR-126-5p/ATAD2 axis
C Liu, J Hou, F Shan, L Wang, H Lu… - OncoTargets and …, 2020 - Taylor & Francis
Background Long non-coding RNA colorectal neoplasia differentially expressed (lncRNA
CRNDE) and microRNA-126-5p (miR-126-5p) were reported to be related to the …
CRNDE) and microRNA-126-5p (miR-126-5p) were reported to be related to the …
Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression
Muscle-invasive bladder carcinomas (MIBCs) are aggressive genitourinary malignancies.
Metastatic urothelial carcinoma of the bladder is generally incurable by current …
Metastatic urothelial carcinoma of the bladder is generally incurable by current …
Deciphering specific miRNAs in brain tumors: a 5-miRNA signature in glioblastoma
MicroRNAs are endogenous non-coding RNAs with a marked impact on the development
and progression of brain tumors. However, they commonly share different expression …
and progression of brain tumors. However, they commonly share different expression …