Role of exosomes in malignant glioma: microRNAs and proteins in pathogenesis and diagnosis
Malignant gliomas are the most common and deadly type of central nervous system tumors.
Despite some advances in treatment, the mean survival time remains only about 1.25 years …
Despite some advances in treatment, the mean survival time remains only about 1.25 years …
[HTML][HTML] Targeting the JAK/STAT pathway in solid tumors
Aberrant activation of signal transducer and activator of transcription (STAT) proteins is
associated with the development and progression of solid tumors. However, as transcription …
associated with the development and progression of solid tumors. However, as transcription …
Prevention and treatment of peri-implant fibrosis by functionally inhibiting skeletal cells expressing the leptin receptor
The cellular and molecular mediators of peri-implant fibrosis—a most common reason for
implant failure and for surgical revision after the replacement of a prosthetic joint—remain …
implant failure and for surgical revision after the replacement of a prosthetic joint—remain …
Hybrid nanofibers based on poly-caprolactone/gelatin/hydroxyapatite nanoparticles-loaded Doxycycline: Effective anti-tumoral and antibacterial activity
R Ramírez-Agudelo, K Scheuermann… - Materials Science and …, 2018 - Elsevier
Cancer is one of the leading causes of morbidity and mortality Worldwide, 19.3 million new
cancer cases are expected to be identified in 2025. Among the therapeutic arsenal to cancer …
cancer cases are expected to be identified in 2025. Among the therapeutic arsenal to cancer …
[HTML][HTML] Exosomes of glioma cells deliver miR-148a to promote proliferation and metastasis of glioblastoma via targeting CADM1
Q Cai, A Zhu, L Gong - Bulletin du cancer, 2018 - Elsevier
Exosomes are now considered to be involved in mediating cell-to-cell communication to
promote or inhibit tumor progression. However, the role and molecular mechanism of …
promote or inhibit tumor progression. However, the role and molecular mechanism of …
Down-regulated lncRNA DLX6-AS1 inhibits tumorigenesis through STAT3 signaling pathway by suppressing CADM1 promoter methylation in liver cancer stem cells
DM Wu, ZH Zheng, YB Zhang, SH Fan… - Journal of Experimental …, 2019 - Springer
Background Liver cancer stem cells (LCSCs) are a small subset of cells characterized by
unlimited self-renewal, cell differentiation, and uncontrollable cellular growth. LCSCs are …
unlimited self-renewal, cell differentiation, and uncontrollable cellular growth. LCSCs are …
miR-21 enhances cardiac fibrotic remodeling and fibroblast proliferation via CADM1/STAT3 pathway
W Cao, P Shi, JJ Ge - BMC cardiovascular disorders, 2017 - Springer
Background Cardiac fibrosis play a key role in the atrial fibrillation pathogenesis but the
underlying potential molecular mechanism is still understood. However, potential …
underlying potential molecular mechanism is still understood. However, potential …
Digesting the role of JAK-STAT and cytokine signaling in oral and gastric cancers
Y Ni, JT Low, J Silke, LA O'Reilly - Frontiers in Immunology, 2022 - frontiersin.org
When small proteins such as cytokines bind to their associated receptors on the plasma
membrane, they can activate multiple internal signaling cascades allowing information from …
membrane, they can activate multiple internal signaling cascades allowing information from …
A five-microRNA signature predicts survival and disease control of patients with head and neck cancer negative for HPV infection
Abstract Purpose: Human papillomavirus (HPV)–negative head and neck squamous cell
carcinoma (HNSCC) is associated with unfavorable prognosis, while independent …
carcinoma (HNSCC) is associated with unfavorable prognosis, while independent …
STAT3 activation as a predictive biomarker for ruxolitinib response in head and neck cancer
Purpose: Increased activity of STAT3 is associated with progression of head and neck
squamous cell carcinoma (HNSCC). Upstream activators of STAT3, such as JAKs, represent …
squamous cell carcinoma (HNSCC). Upstream activators of STAT3, such as JAKs, represent …