Unraveling therapeutic opportunities and the diagnostic potential of microRNAs for human lung cancer

O Sweef, E Zaabout, A Bakheet, M Halawa, I Gad… - Pharmaceutics, 2023 - mdpi.com
Lung cancer is a major public health problem and a leading cause of cancer-related deaths
worldwide. Despite advances in treatment options, the five-year survival rate for lung cancer …

The emerging roles of long noncoding RNAs in lymphatic vascular development and disease

KI Ivanov, OV Samuilova, AA Zamyatnin Jr - Cellular and Molecular Life …, 2023 - Springer
Recent advances in RNA sequencing technologies helped uncover what was once
uncharted territory in the human genome—the complex and versatile world of long …

The long non-coding RNA keratin-7 antisense acts as a new tumor suppressor to inhibit tumorigenesis and enhance apoptosis in lung and breast cancers

Z Zhao, M Meng, J Yao, H Zhou, Y Chen, J Liu… - Cell death & …, 2023 - nature.com
Expression of the long non-coding RNA (lncRNA) keratin-7 antisense (KRT7-AS) is
downregulated in various types of cancer; however, the impact of KRT7-AS deficiency on …

Clinical implications of lncRNA LINC-PINT in cancer

I Bukhari, MR Khan, F Li, B Swiatczak… - Frontiers in Molecular …, 2023 - frontiersin.org
Long noncoding RNAs (lncRNAs) possess the potential for therapeutic targeting to treat
many disorders, including cancers. Several RNA-based therapeutics (ASOs and small …

[HTML][HTML] Decoding LncRNA in COPD: Unveiling Prognostic and Diagnostic Power and Their Driving Role in Lung Cancer Progression

O Sweef, R Mahfouz, T Taşcıoğlu… - International Journal of …, 2024 - mdpi.com
Chronic obstructive pulmonary disease (COPD) and lung cancer represent formidable
challenges in global health, characterized by intricate pathophysiological mechanisms and …

An extensive overview of the role of lncRNAs generated from immune cells in the etiology of cancer

H Luo, H **g, W Chen - International Immunopharmacology, 2024 - Elsevier
Long non-coding RNAs (lncRNAs) are involved in the control of critical tumor-suppressor
and oncogenic pathways in cancer. These types of non-coding RNAs could affect both …

[PDF][PDF] Emerging Bioengineering Approaches for Cancer and Tumor Therapy

HN Majeed, A Ahmad - Science Reviews. Biology, 2024 - sciencereviews.info
Cancer has become a significant socioeconomic burden globally, with millions of new cases
and deaths each year. The promising field of bioengineering has recently undergone …

Knockdown of death receptor 5 antisense long noncoding RNA and cisplatin treatment modulate similar macromolecular and metabolic changes in HeLa cells

DC Gürer, İE Vatansever, Ç Ceylan… - Turkish Journal of …, 2022 - journals.tubitak.gov.tr
Background/aim: Despite great progress in complex gene regulatory mechanisms in the
dynamic tumor microenvironment, the potential contribution of long noncoding RNAs …

Noncoding RNAs in Cancer Theranostics: From Molecular Basis to Therapeutic Implications

Y Tutar - Current Pharmaceutical Biotechnology, 2023 - ingentaconnect.com
Sequencing human genome brought new dimensions to molecular mechanism of
biochemical processes since just a small portion of the genome is translated into protein but …

Long non‐coding RNA‐mediated modulation of endoplasmic reticulum stress under pathological conditions

YC Çiftçi, Y Yurtsever, B Akgül - Journal of Cellular and …, 2024 - Wiley Online Library
Endoplasmic reticulum (ER) stress, which ensues from an overwhelming protein folding
capacity, activates the unfolded protein response (UPR) in an effort to restore cellular …